Evidence map›Paper›PMID 30539906›Full record

ArticleChinese medical journal2018

Clinical Features and Prognostic Risk Factors of Choroid Plexus Tumors in Children.

Wen-Jian-Long Zhou, Xi Wang, Jia-Yi Peng, Shun-Chang Ma, Dai-Nan Zhang, Xiu-Dong Guan, Jin-Fu Diao, Jian-Xing Niu, Chun-De Li, Wang Jia

Open access · goldAbstract read
In one paragraph

Article in Chinese medical journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 30 citations in OpenAlex.

  1. Giant cystic choroid plexus papilloma mimicking intracerebral hydatid cyst.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2026
    Article
  2. Article
  3. Predictive factors in the management of hydrocephalus and cerebrospinal fluid-related complications in pediatric choroid plexus tumors: a single-center experience.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2025
    Article
  4. Choroid plexus tumors in adults: a retrospective mono-institutional study.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
    Article
  5. Article
  6. Article
  7. Tumor-related hydrocephalus in infants: a narrative review.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2021
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Choroid Plexus Papilloma - Case Presentation.Current health sciences journal
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Wen-Jian-Long ZhouDepartment of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing 100050, China.
Xi WangDepartment of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing 100050, China.
Jia-Yi PengDepartment of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing 100050, China.
Shun-Chang MaDepartment of Neurosurgery, Beijing Neurosurgical Institute, Capital Medical University, Beijing 100050, China.
Dai-Nan ZhangDepartment of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing 100050, China.
Xiu-Dong GuanDepartment of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing 100050, China.
Jin-Fu DiaoDepartment of Neurosurgery, Beijing Tiantan Hospital; Department of Neurosurgery, Beijing Neurosurgical Institute, Capital Medical University, Beijing 100050, China.
Jian-Xing NiuDepartment of Neurosurgery, Beijing Armed Police General Hospital, Beijing 100000, China.
Chun-De LiDepartment of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing 100050, China.
Wang JiaDepartment of Neurosurgery, Beijing Tiantan Hospital; Department of Neurosurgery, Beijing Neurosurgical Institute, Capital Medical University, Beijing 100050, China.
Beijing Tian Tan Hospital · CNCapital Medical University · CNBeijing Institute of Neurosurgery · CNChinese People's Armed Police General Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDecision-making concerning the treatment of choroid plexus tumor (CPT) in pediatric patients remains a topic of considerable debate. The aim of this work was to describe clinical features and prognostic risk factors of CPT in the pediatric population and to provide theoretical opinions regarding clinical decisions for CPT.

methodsThe data of 96 patients with CPT and younger than 14 years were retrospectively analyzed. Clinical characteristics such as pathological type of CPTs, rate and severity of hydrocephalus, treatment and outcome, and recurrence were investigated. For categorical variables, the Pearson's Chi-square test was performed. The Mann-Whitney U-test was used for comparisons between nonnormally distributed parameters. Log-rank test was used for progression-free survival (PFS).

resultsThe study included 70 choroid plexus papilloma (CPP) cases, 17 atypical choroid plexus papilloma (aCPP) cases, and 9 choroid plexus carcinoma (CPC) cases. Compared with patients with CPP or aCPP, patients with CPC had a shorter disease course (median: CPP, 4 months; aCPP, 2 months; CPC, 1 month; H: 23.5, P < 0.001), higher rate of acute hydrocephalus (CPP, 27.1%; aCPP, 52.9%; CPC, 77.8%; χ

conclusionsOur results indicated that CPP in the fourth ventricle could trigger serious clinical symptoms at an early stage, requiring early intervention. Adjuvant treatment might be necessary for patients with partially resected CPP, aCPP, and CPC to achieve a favorable outcome.

Indexed as

ChildChild, PreschoolChoroid Plexus NeoplasmsFemaleHumansHydrocephalusInfantMaleNeoplasm MetastasisNeoplasm Recurrence, LocalPrognosisRisk FactorsAtypical Choroid Plexus PapillomaChoroid Plexus CarcinomaChoroid Plexus PapillomaPediatric Patients

Identifiers

PMID30539906
PMCPMC6302644
OpenAlexW2904756459

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.