Evidence map›Paper›PMID 30539411›Full record

Trial reportLa Radiologia medica2019

Diagnostic efficacy of model-based iterative reconstruction algorithm in an assessment of coronary artery in comparison with standard hybrid-Iterative reconstruction algorithm: dose reduction and image quality.

Davide Ippolito, Luca Riva, Cammillo R Talei Franzesi, Cecilia Cangiotti, Andrea De Vito, Filiberto Di Gennaro, Gabriele D'andrea, Andrea Crespi, Sandro Sironi

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in La Radiologia medica, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Davide IppolitoDepartment of Diagnostic Radiology, San Gerardo Hospital, University of Milano-Bicocca, Via Pergolesi 33, 20900, Monza, MB, Italy. davideatena@tiscalinet.it.
Luca RivaDepartment of Diagnostic Radiology, San Gerardo Hospital, University of Milano-Bicocca, Via Pergolesi 33, 20900, Monza, MB, Italy.
Cammillo R Talei FranzesiDepartment of Diagnostic Radiology, San Gerardo Hospital, University of Milano-Bicocca, Via Pergolesi 33, 20900, Monza, MB, Italy.
Cecilia CangiottiDepartment of Diagnostic Radiology, San Gerardo Hospital, University of Milano-Bicocca, Via Pergolesi 33, 20900, Monza, MB, Italy.
Andrea De VitoDepartment of Diagnostic Radiology, San Gerardo Hospital, University of Milano-Bicocca, Via Pergolesi 33, 20900, Monza, MB, Italy.
Filiberto Di GennaroDepartment of Diagnostic Radiology, San Gerardo Hospital, University of Milano-Bicocca, Via Pergolesi 33, 20900, Monza, MB, Italy.
Gabriele D'andreaDepartment of Diagnostic Radiology, San Gerardo Hospital, University of Milano-Bicocca, Via Pergolesi 33, 20900, Monza, MB, Italy.
Andrea CrespiSchool of Medicine, University of Milano-Bicocca, Via Cadore 48, 20900, Monza, MB, Italy.
Sandro SironiSchool of Medicine, University of Milano-Bicocca, Via Cadore 48, 20900, Monza, MB, Italy.
University of Milano-Bicocca · ITOspedale Papa Giovanni XXIII · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate the image quality and radiation dose exposure of low-dose coronary CTA (cCTA) study, reconstructed with the new model-based iterative reconstruction algorithm (IMR), compared with standard hybrid-iterative reconstruction (iDose MATERIALS AND

methodsNinety-eight patients with an indication for coronary CT study were prospectively enrolled. Fifty-two patients (study group) underwent 256-MDCT low-dose cCTA (80 kV; automated-mAs; 60 mL of CM, 350 mgL/mL) with prospective ECG-triggering acquisition and IMR. A control group of 46 patients underwent 256-MDCT standard prospective ECG-gated protocol (100 kV; automated-mAs; 70 mL of CM, 400 mgL/mL; iDose

resultsMean values of mAs were significantly lower for IMR-cCTA (167 ± 62 mAs) compared to iDose-cCTA (278 ± 55 mAs), p < 0.001. With a significant reduction of 38% in radiation dose exposure (DLP: IMR-cCTA 91.7 ± 26 mGy cm vs. iDose-cCTA 148.6 ± 35 mGy cm; p value < 0.001), despite the use of different CM, we found higher mean attenuation values of the coronary arteries in IMR group compared to iDose

conclusionsLow-dose cCTA study combined with IMR reconstruction allows to correctly evaluate coronary arteries disease, offering high-quality images and significant radiation dose exposure reduction (38%), as compared to standard cCTA protocol.

Indexed as

AlgorithmsAgedAged, 80 and overCardiac-Gated Imaging TechniquesComputed Tomography AngiographyContrast MediaCoronary AngiographyCoronary Artery DiseaseFemaleHumansIohexolMaleMiddle AgedProspective StudiesRadiation DosageRadiographic Image Interpretation, Computer-AssistedContrast MediaiobitridolIohexolCardiac CT angiographyLow contrast mediumLow-kVLow radiation doseModel-based iterative reconstruction

Identifiers

PMID30539411
OpenAlexW2905483920

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.