Trial reportHeart and vessels2019
Artificial FLOwering plants in Reducing Anxiety and depressive symptoms following Acute Coronary Syndromes (A-FLORA-ACS): a randomised controlled trial.
Trial report in Heart and vessels, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed, 6 citations in OpenAlex.
- Anxiety disorders following percutaneous coronary intervention for acute myocardial infarction: A comprehensive review of clinical manifestations and interventions.World journal of psychiatry · 2025Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Patients often experience emotional distress after acute coronary syndrome (ACS). These may lead to symptoms of depression or anxiety and greater morbidity/mortality. We sought to determine whether flowering plants in the coronary care ward reduced depressive and anxiety symptoms in these patients. Patients with ACS were randomly allocated to flowering plants (intervention) or no plants (control) in their room during index hospitalisation. Baseline data were collected. The primary outcome was the Hospital Anxiety and Depression Scale (HADS) depressive and anxiety symptom scores at discharge. Secondary outcomes were HADS depression and anxiety scores at 3 months. Both modified intention-to-treat (mITT) and per-protocol (PP) analysis were performed. 122 patients were included in the analysis after case exclusion, with all completing the HADS questionnaire at discharge and 89/122 (73%) patients completing the 3-month post-discharge HADS. At discharge, mean depressive symptom scores were lower in the intervention group, but only significantly so in the PP analysis (mITT 3.6/21 vs 4.6/21, p = 0.11; PP 3.5/21 vs 4.9/21, p = 0.04). There were no significant changes in between-group anxiety symptom scores (mITT 6.4/21 vs 6.1/21, p = 0.51; PP 3.3/21 vs 3.6/21, p = 0.67). The mean increase in depressive symptom scores at 3 months was smaller in the intervention group in both analyses (mITT 0.6 ± 3.6 vs 2.2 ± 2.6, p = 0.02; PP 0.8 ± 3.6 vs 2.4 ± 2.7, p = 0.03). Mean increase in anxiety symptom scores was not significantly different between groups (mITT 2.8/21 vs 2.5/21, p = 0.86; PP 3.3/21 vs 3.6/21, p = 0.67). Flowering plants during index hospitalisation for ACS reduced depressive symptoms in a per-protocol analysis but did not have a significant impact on anxiety symptoms. Increases in depression symptom scores were significantly smaller at 3 months post exposure to flowers compared to anxiety symptom scores.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.