Evidence map›Paper›PMID 30539002›Full record

ArticleBioMed research international2018

A Novel

Yanni Zhang, Huishuang Chen, Zhiyu Peng, Santasree Banerjee, Wei Li, Zhaolong Zhao, Jianbin Sun, Jian Lv, Hui Huang, Ru Bai and 2 more

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Yanni ZhangSecond Department of Surgery, Hebei Medical University Fourth Affiliated Hospital and Hebei Provincial Tumor Hospital, 12 Jiankang Road, Shijiazhuang, Hebei 050011, China.
Huishuang ChenBGI Genomics, BGI-Shenzhen, Shenzhen 518083, China.
Zhiyu PengBGI Genomics, BGI-Shenzhen, Shenzhen 518083, China.
Santasree BanerjeeBGI Genomics, BGI-Shenzhen, Shenzhen 518083, China.
Wei LiBGI Genomics, BGI-Shenzhen, Shenzhen 518083, China.
Zhaolong ZhaoSecond Department of Surgery, Hebei Medical University Fourth Affiliated Hospital and Hebei Provincial Tumor Hospital, 12 Jiankang Road, Shijiazhuang, Hebei 050011, China.
Jianbin SunSecond Department of Surgery, Hebei Medical University Fourth Affiliated Hospital and Hebei Provincial Tumor Hospital, 12 Jiankang Road, Shijiazhuang, Hebei 050011, China.
Jian LvSecond Department of Surgery, Hebei Medical University Fourth Affiliated Hospital and Hebei Provincial Tumor Hospital, 12 Jiankang Road, Shijiazhuang, Hebei 050011, China.
Hui HuangBGI Genomics, BGI-Shenzhen, Shenzhen 518083, China.
Ru BaiBGI Genomics, BGI-Shenzhen, Shenzhen 518083, China.
Keke LinBGI Genomics, BGI-Shenzhen, Shenzhen 518083, China.
Zhongxin LiSecond Department of Surgery, Hebei Medical University Fourth Affiliated Hospital and Hebei Provincial Tumor Hospital, 12 Jiankang Road, Shijiazhuang, Hebei 050011, China.ORCID 0000-0002-6375-1667
BGI Group (China) · CNHebei Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lynch syndrome is a genetically and clinically heterogeneous disorder; it is caused by a germline mutation in DNA mismatch repair (MMR) genes. Individuals with a heterozygous mutation in MLH1 have an increased risk for developing colorectal cancer. Here we described a 5-generation Chinese Lynch syndrome family with different severity and onset age. A novel heterozygous germline mutation (c.3G>T, p.Met1Ile) in

Indexed as

Gene Expression RegulationGenetic Predisposition to DiseaseAdultAge of OnsetAsian PeopleBase SequenceCodon, InitiatorColorectal Neoplasms, Hereditary NonpolyposisFamilyFemaleHumansMaleMiddle AgedMutationMutL Protein Homolog 1PedigreeCodon, InitiatorMLH1 protein, humanMutL Protein Homolog 1RNA, Messenger

Identifiers

PMID30539002
PMCPMC6261076
OpenAlexW2900706312

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.