Volumetric trends of progressive in-field recurrences after stereotactic radiosurgery of metastatic intracranial tumors.

Purvee D Patel, Eric L Hargreaves, Adnan F Danish, Joseph Weiner, Shabbar F Danish

Abstract read

In one paragraph

Article in Journal of radiosurgery and SBRT, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Purvee D PatelDepartment of Neurological Surgery, Rutgers University, Robert Wood Johnson Medical School, New Brunswick, NJ, 08901, USA.

Eric L HargreavesDepartment of Neurological Surgery, Rutgers University, Robert Wood Johnson Medical School, New Brunswick, NJ, 08901, USA.

Adnan F DanishSummit Medical Group, MD Anderson Cancer Center, Florham Park, NJ, 07932, USA.

Joseph WeinerDepartment of Radiation Oncology, Rutgers University, Robert Wood Johnson University Hospital, New Brunswick, NJ 08901, USA.

Shabbar F DanishDepartment of Neurological Surgery, Rutgers University, Robert Wood Johnson Medical School, New Brunswick, NJ, 08901, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveLocal recurrence after stereotactic radiosurgery for brain metastasis is a well-known problem. We analyzed volumetric trends from the time of radiosurgery to time of treatment to understand progression behavior.

methodsA retrospective review of patients who underwent treatment for post-radiation progressive lesions was performed. Volumetric trends were obtained by plotting individual lesion volumes from the post-radiation nadir volume to volume at treatment and then fitted to exponential decay or linear regressions.

resultsTwenty-eight post-radiation recurrences demonstrated exponential growth and thirteen followed a linear pattern. For lesions exhibiting exponential growth, the average nadir volume was 0.26cm

conclusionsExponential and linear regressions are accurate representations of post-radiation progression behavior and may be valuable in understanding the growth patterns for recurrences ultimately requiring treatment.

Indexed as

progressive in-field recurrencestereotactic radiosurgery

Identifiers

PMID30538890

PMCPMC6255718

What OpenQuestion holds

Textmetadata

Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.