Evidence map›Paper›PMID 30538509›Full record

ArticleInfection and drug resistance2018

Declining prevalence of hepatitis C virus among university students in one of the main governorates in Egypt.

Yousry Esam-Eldin Abo-Amer, Sherief Abd-Elsalam, Hazim Eldosoky, Amira K ELShenawy, Shereen Awny, Waleed Elagawy, Mohamed El Abgeegy, Heba Fadl Elsergany, Heba Elashry, Manal Saad Negm

Abstract read
In one paragraph

Article in Infection and drug resistance, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yousry Esam-Eldin Abo-AmerHepatology, Gastroenterology and Infectious Diseases Department, Mahala Hepatology Teaching Hospital, Gharbia, Egypt.
Sherief Abd-ElsalamTropical Medicine Department, Tanta University, Tanta, Egypt, Sherif_tropical@yahoo.com.
Hazim EldosokyClinical Pathology Department, Student Hospital, Menoufia University, Menoufia, Egypt.
Amira K ELShenawyPublic Health and Community Medicine Department, Tanta University, Tanta, Egypt.
Shereen AwnyInternal Medicine Department, Tanta University, Tanta, Egypt.
Waleed ElagawyTropical Medicine Department, National Hepatology and Tropical Medicine Research Institute in Cairo, Cairo, Egypt.
Mohamed El AbgeegyTropical Medicine Department, National Hepatology and Tropical Medicine Research Institute in Cairo, Cairo, Egypt.
Heba Fadl ElserganyTropical Medicine Department, National Hepatology and Tropical Medicine Research Institute in Cairo, Cairo, Egypt.
Heba ElashryTropical Medicine Department, Tanta University, Tanta, Egypt, Sherif_tropical@yahoo.com.
Manal Saad NegmInternal Medicine Department, Tanta University, Tanta, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimsEgypt is considered to have the highest rate of hepatitis C virus (HCV) prevalence worldwide. However, HCV prevalence is currently declining due to the improvement of health education programs, improved environmental sanitation, and the introduction of novel treatment regimens. The aim of this work was to determine the HCV seroprevalence among Menoufia University students.

methodsThe current study included 48,972 students from Menoufia University, Egypt. Blood sample was obtained from every patient for HCV seromarker testing. In anti-HCV-positive subjects, quantitative PCR for HCV RNA was done.

resultsOverall, HCV antibody prevalence rate was 1%. This prevalence was higher in females (304/27,421; 1.1%) than in males (194/21,371; 0.9%). HCV-RNA PCR was positive in 355/48,972 (0.7%); the percentage of HCV PCR positive among the anti-HCV-positive was 71.3% (355/498 patients), with a higher prevalence among females than in males but without statistical significance. In addition, rural areas showed more prevalent HCV seroprevalence than urban areas.

conclusionThese prevalence rates for HCV infection are lower than that previously reported in the same age group denoting a new evidence for the reduction of prevalence and a hope for successful eradication of HCV in the forthcoming years.

Indexed as

DAAdirect acting antiviralEgypteradicationHCVhepatitis C virusinfectionMenoufia Universityprevalencestudentstreatment

Identifiers

PMID30538509
PMCPMC6254504

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.