Evidence map›Paper›PMID 30538507›Full record

ArticleInfection and drug resistance2018

Epidemiological characteristics and genetic structure of linezolid-resistant

Meijuan Chen, Hongying Pan, Yaling Lou, Zhe Wu, Jiajie Zhang, Yicheng Huang, Wei Yu, Yunqing Qiu

Open access · goldAbstract read
In one paragraph

Article in Infection and drug resistance, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 39 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Linezolid in the Focus of Antimicrobial Resistance ofInternational journal of molecular sciences · 2025
    Review
  6. Article
  7. Article
  8. Molecular Characterization of Linezolid-Non-SusceptibleInfection and drug resistance · 2025
    Article
  9. The Impact ofPathogens (Basel, Switzerland) · 2024
    Review
  10. Risk factors and outcome associated with the acquisition of MDR linezolid-resistant Enterococcus faecium: a report from tertiary care centre.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2024
    Article
  11. Article
  12. Prevalence and Associated Factors ofAntibiotics (Basel, Switzerland) · 2023
    Article
  13. High occurrence ofEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2023
    Article
  14. Article
  15. Antimicrobial Susceptibility ofAntibiotics (Basel, Switzerland) · 2022
    Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Meijuan ChenDepartment of Infectious Diseases, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou, China, wyu@zju.edu.cn.
Hongying PanDepartment of Infectious Diseases, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou, China, wyu@zju.edu.cn.
Yaling LouDepartment of Infectious Diseases, Dongyang People's Hospital, Jinhua, China.
Zhe WuState Key Laboratory for Diagnosis and Treatment of Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China, wyu@zju.edu.cn, qiuyq@zju.edu.cn.
Jiajie ZhangDepartment of Infectious Diseases, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou, China, wyu@zju.edu.cn.
Yicheng HuangDepartment of Infectious Diseases, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou, China, wyu@zju.edu.cn.
Wei YuDepartment of Infectious Diseases, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou, China, wyu@zju.edu.cn.
Yunqing QiuState Key Laboratory for Diagnosis and Treatment of Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China, wyu@zju.edu.cn, qiuyq@zju.edu.cn.
Zhejiang Provincial People's Hospital · CNState Key Laboratory of Diagnosis and Treatment of Infectious DiseasesWenzhou Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe aim of this study was to investigate the mechanism of linezolid resistance and evaluate the risk factors for linezolid-resistant

methodsA total of 730

resultsTwenty-six LZR-Efa were isolated from various clinical samples, and 24 isolates were multidrug resistant. Four isolates were daptomycin nonsusceptible, while all LZR-Efa were susceptible to vancomycin. Thirteen different sequence types (STs) were identified, and the most prevalent type was ST16 (23.1%). The genes

conclusionThe main trends of LZR-Efa, with lower level of resistance, were sporadic mainly in the department of surgery.

Indexed as

linezolidresistance mechanismrisk factorsvirulent factors

Identifiers

PMID30538507
PMCPMC6251436
OpenAlexW2900501232

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.