Evidence map›Paper›PMID 30538325›Full record

ArticleJournal of perinatology : official journal of the California Perinatal Association2019

While waiting for a vaccine: opportunities for optimization of neonatal group B streptococcal (GBS) disease prevention in Israel.

Dan Waisman, Ayala Gover, Michal Molad, Reuven Kedar, Avi Rotschild, William E Benitz

Abstract read
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In one paragraph

Article in Journal of perinatology : official journal of the California Perinatal Association, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Dan WaismanDepartment of Neonatology, Carmel Medical Center and Faculty of Medicine, Technion - Israel Institute of Technology, 7 Michal St, Haifa, Israel. dwaisman@technion.ac.il.ORCID http://orcid.org/0000-0002-6768-0042
Ayala GoverDepartment of Neonatology, Carmel Medical Center and Faculty of Medicine, Technion - Israel Institute of Technology, 7 Michal St, Haifa, Israel.
Michal MoladDepartment of Neonatology, Carmel Medical Center and Faculty of Medicine, Technion - Israel Institute of Technology, 7 Michal St, Haifa, Israel.
Reuven KedarDepartment of Obstetrics and Gynecology, Carmel Medical Center, and Faculty of Medicine, Technion - Israel Institute of Technology, Michal St, Haifa, Israel.
Avi RotschildDepartment of Neonatology, Carmel Medical Center and Faculty of Medicine, Technion - Israel Institute of Technology, 7 Michal St, Haifa, Israel.
William E BenitzStanford University School of Medicine, Division of Neonatal & Developmental Medicine, Palo Alto, CA, 94304, USA.
Technion – Israel Institute of Technology · ILStanford University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo quantify effects of different strategies for decreasing neonatal early onset GBS sepsis (EOGBS) in Israel. STUDY

designA risk allocation model for EOGBS among infants ≥ 35w was adapted to Israeli data. Effects of strategies for antepartum (APS) and intrapartum (IPS) screening, and intrapartum (IAP) and/or postpartum antibiotic prophylaxis (PAP) were calculated.

resultsEstimated EOGBS attack rates (AR) with APS in 90%, IAP in 90%, may reduce AR to 0.18/1000. A rapid intrapartum test would further decrease AR to 0.16/1000, while reducing IAP from 21.3 to 12.5% of women. For babies with risk factors and GBS+ who do not receive IAP, further risk reduction could be achieved by PAP.

conclusionIAP remains the main intervention to decrease EOGBS. IAP and PAP together may reduce EOGBS present incidence by 40%. Combining rapid intrapartum screening with selective IAP and selective PAP for remaining gaps, would be the most efficient strategy.

Indexed as

Antibiotic ProphylaxisFemaleHumansIncidenceInfant, NewbornInfectious Disease Transmission, VerticalIsraelPregnancyPregnancy Complications, InfectiousRisk FactorsRisk Reduction BehaviorStreptococcal InfectionsStreptococcus agalactiaeVaccinesVaccines

Identifiers

PMID30538325
OpenAlexW2904165069

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.