ArticleThe British journal of ophthalmology2019
Evaluation of vascular changes in intermediate uveitis and retinal vasculitis using swept-source wide-field optical coherence tomography angiography.
Article in The British journal of ophthalmology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02811536 (Investigation of Vascular Pathology in Eye Diseases Using Using Optical Coherence Tomography Angiography), which is not on this map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Investigation of Vascular Pathology in Eye Diseases Using Using Optical Coherence Tomography Angiography (OCT-A)
Who cites it
20 citing papers in PubMed, 57 citations in OpenAlex.
- The expanding horizon: Role of widefield imaging in uveitis.Indian journal of ophthalmology · 2026Review
- Advanced Multimodal Imaging in Granulomatous Uveitis: From Differential Diagnosis to Treatment Monitoring and Surgical Integration.Journal of clinical medicine · 2026Review
- Diagnosis and Monitoring of Retinal Vasculitis by Widefield Swept Source OCT Angiography.Diagnostics (Basel, Switzerland) · 2025Article
- Widefield OCT angiography.Progress in retinal and eye research · 2025Review
- Vessel density on optical coherence tomography angiography is prognostic for future disease course in intermediate uveitis.Scientific reports · 2024Article
- Commentary: Optical coherence angiography in intermediate uveitis: What is the scope?Indian journal of ophthalmology · 2023Article
- A systematic review of OCT and OCT angiography in retinal vasculitis.Journal of ophthalmic inflammation and infection · 2023Review
- Macular vessel densities by optical coherence tomography angiography in patients with intermediate uveitis.Indian journal of ophthalmology · 2023Article
- Microvascular changes in the recurrent cystoid macular edema secondary to posterior noninfectious uveitis on optical coherence tomography angiography.International ophthalmology · 2022Observational
- Retinal optical coherence tomography angiography findings of acute anterior uveitis.International ophthalmology · 2022Article
- Dynamics of Retinal Vessel Loss After Acute Optic Neuritis in Patients With Relapsing Multiple Sclerosis.Neurology(R) neuroimmunology & neuroinflammation · 2022Article
- Comparison of Indocyanine Green Angiography and Swept-Source Wide-Field Optical Coherence Tomography Angiography in Posterior Uveitis.Frontiers in medicine · 2022Article
- Research progress on the application of optical coherence tomography in the field of oncology.Frontiers in oncology · 2022Review
- Microvasculature Features of Vogt-Koyanagi-Harada Disease Revealed by Widefield Swept-Source Optical Coherence Tomography Angiography.Frontiers in medicine · 2021Article
- Agonistic autoantibodies against ß2-adrenergic receptor influence retinal microcirculation in glaucoma suspects and patients.PloS one · 2021Article
- Comparison of wide-field swept source optical coherence tomography angiography and fundus autofluorescence in tubercular serpiginous-like choroiditis.Indian journal of ophthalmology · 2020Article
- Clinical and Optical Coherence Tomography Angiographic Features in Patients with PostcataractJournal of ophthalmology · 2020Article
- An Unusual Retinal Vessel Modification in Patients Affected by JIA-Uveitis with a Follow-Up Longer Than 16 Years.Case reports in ophthalmological medicine · 2020Article
- Optical coherence tomography angiography (OCTA) as a new diagnostic tool in uveitis.Journal of ophthalmic inflammation and infection · 2019Review
- Optical coherence tomography angiography in diabetic retinopathy: a review of current applications.Eye and vision (London, England) · 2019Review
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo evaluate vascular changes in patients with intermediate uveitis with or without retinal vasculitis using swept-source wide-field optical coherence tomography angiography (OCTA).
methodsThis is a prospective cross-sectional study. Consecutive patients with intermediate uveitis were evaluated using wide-field OCTA. Wide-field OCTA and en-face OCT images were analysed for the presence of capillary non-perfusion and reduced perfusion, disruption of ellipsoid zone, and abnormalities on en-face wide-field retinal thickness maps, respectively, and compared with fluorescein angiography (FA) findings in a subcohort.
results164 eyes of 88 patients with intermediate uveitis were included. Areas of capillary non-perfusion and reduced perfusion were more frequently observed in the choroidal OCTA slab (33.3% and 49.4%), choriocapillaris (CC; 31.4% and 48%) and deep capillary plexus (DCP; 9.6% and 34.6%) than in the superficial capillary plexus (SCP; 5% and 26.3%), respectively. Intermediate uveitis with vasculitis presented more frequently with non-perfusion and hypoperfusion in the DCP (p=0.003 and p=0.05, respectively) and SCP (p=0.007 and p=0.005, respectively) than intermediate uveitis without vasculitis. Peripheral capillary leakage on FA correlated with the presence of perivascular, macular and generalised thickening on en-face wide-field thickness maps (p=0.007). Ischaemia on FA was significantly associated with non-perfusion on wide-field OCTA in SCP and DCP (p=0.019 and p=0.027, respectively).
conclusionChanges in the choroid, CC and DCP are more frequently found than in the SCP on wide-field OCTA in intermediate uveitis. While wide-field OCTA is a reliable tool to detect capillary non-perfusion in intermediate uveitis, it was not helpful in determining disease activity. TRIAL REGISTRATION NUMBER: NCT02811536.
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