ReviewBMC geriatrics2018
An overview of co-morbidities and the development of pressure ulcers among older adults.
Review in BMC geriatrics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06726486 (Use of a Hypercaloric and Hyperprotein Supplement Enriched with Immunonutrients in Multi-pathological Malnourished Patients to Improve the Incidence and Prevalence of Pressure Sores), which is not on this map. Cited by 116 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Use of a Hypercaloric and Hyperprotein Supplement Enriched with Immunonutrients in Multi-pathological Malnourished Patients to Improve the Incidence and Prevalence of Pressure Sores: a Randomized Controlled Trial
Who cites it
116 citing papers in PubMed, 4 syntheses or guidelines pooled it, 353 citations in OpenAlex.
- Prevalence of pressure ulcer and associated factors in Ethiopia: a systematic review and meta-analysis.BMC public health · 2025Pooled it
- Causal effect of obesity and adiposity distribution on the risk of pressure ulcers and potential mediation by type 2 diabetes mellitus: insights from multivariable mendelian randomization and mediation analysis.Archives of dermatological research · 2024Pooled it
- A systematic review of nurses' knowledge and related factors towards the prevention of medical device-related pressure ulcers.International wound journal · 2023Pooled it
- A systematic review of clinical practice guidelines and other best practice recommendations for pressure injury risk assessment in the United States.Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair SocietyPooled it
- Trial
- Bedtime vs Morning Antihypertensive Medications in Frail Older Adults: The BedMed-Frail Randomized Clinical Trial.JAMA network open · 2025Trial
- Phase I/IIa Feasibility Trial of Autologous Quality- and Quantity-Cultured Peripheral Blood Mononuclear Cell Therapy for Non-Healing Extremity Ulcers.Stem cells translational medicine · 2022Trial
- Risk factors for community-acquired pressure injuries: Findings from a large-scale Asian case-control study.International journal of nursing studies advances · 2026Article
- Examining Risk Factors for Pressure Injury Development Among Nursing Home Residents: A Retrospective Study.Journal of clinical nursing · 2026Article
- Association Between Charlson Comorbidity Index and Pressure Injury Stage: A Retrospective Cohort Study.International wound journal · 2026Article
- Prehabilitation for Pressure Ulcer Surgery: A Practical and Evidence-based Guide.Plastic and reconstructive surgery. Global open · 2026Article
- The Multidimensional Impact of Traditional Orthopaedic Casting and the Role of Emerging Immobilization Technologies: A Narrative Review.Healthcare (Basel, Switzerland) · 2026Review
- Relatively upstream factors associated with pressure injury occurrence and staging in older hospitalized patients: a prospective observational study.BMC geriatrics · 2026Observational
- Effect of Sodium-Glucose Cotransporter-2 Inhibitors on Frailty in Patients with Heart Failure.Internal medicine (Tokyo, Japan) · 2026Article
- Predictors of Pressure Injuries in Older Residents Living in Nursing Homes in Sri Lanka: A Prospective Multi-Site Cohort Study.Journal of advanced nursing · 2026Observational
- Impact of pressure ulcers and frailty on long-term mortality: a prospective cohort study of hospitalized older adults.European geriatric medicine · 2026Article
- VALENF-Instrument-Based Nursing Assessment and Early Occurrence of Hospital-Acquired Pressure Injuries and Falls Among Hospitalized Adults.Nursing reports (Pavia, Italy) · 2026Article
- Health-Related Quality of Life and Mobility Levels in ICU Survivors with Heel Pressure Ulcer: An Observational Study.Nursing reports (Pavia, Italy) · 2026Article
- The Spectrum of Motor Disorders in Patients with Chronic Kidney Disease: Pathogenic Mechanisms, Clinical Manifestations, and Therapeutic Strategies.Journal of clinical medicine · 2026Review
- Article
56 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe prevalence of pressure ulcers particularly in the frail older adult population continues to be high and very costly especially in those suffering from chronic diseases and has brought a higher awareness to comprehensive, preventive and therapeutic measures for treatment of pressure ulcers. Internal risk factors highlighted by comorbidities play a crucial role in the pathogenesis of pressure ulcers. MAIN BODY: Focusing on the impact of common chronic diseases (comorbidities) in aging on pressure ulcers (e.g., cardiovascular diseases, diabetes, chronic pulmonary diseases, renal diseases and neurodegenerative disorders) and the significant complicating conditions e.g., anemia, infectious diseases, malnutrition, hospitalization, incontinence and polypharmacy, frailty and disability becomes important in developing a more complete, inclusive and multidisciplinary approach to prevention of PU in older patients.
objectiveTo describe chronic and acute conditions which are risk factors in elderly patients for developing PU.
methodsWe present an overview of comorbidities seen with PU in three diverse patient locations. The inclusion criteria are sites (community, acute hospital and long term facilities), older patients, chronic diseases and pressure ulcers grade 2 and over. Using a recently developed conceptual framework accepted by European and National Pressure Ulcer Advisory Panels, we examined chronic diseases to identify the risk factors of chronic conditions and complicating conditions which potentially influence risk for PU development.
conclusionMultiple chronic diseases and complicating factors which associated with immobility, tissue ischemia, and undernutrition are caused to PU in community settings, hospitals, and nursing facilities.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.