ReviewExperimental biology and medicine (Maywood, N.J.)2018
Body composition and mortality in the general population: A review of epidemiologic studies.
Review in Experimental biology and medicine (Maywood, N.J.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
50 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Association Between Fat-Free Mass and Mortality: A Systematic Review and Meta-Analysis.Journal of cachexia, sarcopenia and muscle · 2026Pooled it
- Low lean mass and all-cause mortality risk in the middle-aged and older population: a dose-response meta-analysis of prospective cohort studies.Frontiers in medicine · 2025Pooled it
- Body Composition and Intradialytic Exercise in Kidney Disease: A Combined Analysis of the PEDAL and CYCLE-HD Randomised Controlled Trials.Journal of cachexia, sarcopenia and muscle · 2025Trial
- Effectiveness of a 12-Month Online Weight Reduction Program in Cohorts with Different Baseline BMI-A Prospective Cohort Study.Nutrients · 2022Trial
- The Vicious Cycle of Inflammation: How Obesity, Dialysis Catheters, and NETosis Determine Albumin Levels and Prognosis in Hemodialysis Patients.International journal of molecular sciences · 2026Article
- Estimating the effect of hypothetical dietary protein interventions on changes in body composition of postmenopausal women over 3 years using data from the Women's Health Initiative (WHI) Study: an emulated target trial.International journal of obesity (2005) · 2026Article
- Epigenetic age and cardiometabolic disease in Guatemalan adults: a cross-sectional analysis.Journal of health, population, and nutrition · 2026Article
- Body Composition Changes After Bariatric Surgery or Treatment With GLP-1 Receptor Agonists.JAMA network open · 2026Article
- Machine learning-based estimation of trunk fat percentage and its association with cardiometabolic risk leveraging two large national cohorts.Frontiers in nutrition · 2026Article
- Impact of lean body mass index on short-term outcomes in patients with ischemic stroke: an observational cohort study.Scientific reports · 2025Observational
- Is BMI Enough? Body Composition Profiles and Cardiometabolic Risk in Hmar Tribe of Northeast India.Journal of racial and ethnic health disparities · 2025Article
- Impact of Alcohol Intake on Body Composition in Patients with Steatotic Liver Disease.Nutrients · 2025Article
- The association between the healthy lifestyle index and MRI-derived body composition measurements in the UK Biobank study.Scientific reports · 2025Article
- Types of Complications and Associated Factors in Patients Undergoing Permanent Cardiac Pacemaker Implantation: A Systematic Review.Journal of multidisciplinary healthcare · 2025Review
- The Interactive Effects of Sedentary Time, Physical Activity, and Fat Mass on Insulin Resistance in the Young Population.The Journal of clinical endocrinology and metabolism · 2024Observational
- Effects of a Six-Month Physical Activity Program on Health Risk Factors and Body Composition Among Overweight and Obese Middle-Aged Adults.Healthcare (Basel, Switzerland) · 2024Article
- Abdominal Body Composition Reference Ranges and Association With Chronic Conditions in an Age- and Sex-Stratified Representative Sample of a Geographically Defined American Population.The journals of gerontology. Series A, Biological sciences and medical sciences · 2024Article
- Diet and Lifestyle Intervention-Induced Pattern of Weight Loss Related to Reduction in Low-Attenuation Coronary Plaque Burden.Diagnostics (Basel, Switzerland) · 2024Article
- Transforming body composition with semaglutide in adults with obesity and type 2 diabetes mellitus.Frontiers in endocrinology · 2024Article
- Clinical Significance of Nutritional Status, Inflammation, and Body Composition in Elderly Hemodialysis Patients-A Case-Control Study.Nutrients · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
impact statementCurrent understanding of the association of body composition on mortality in the general population is limited. This review evaluated the available epidemiologic studies on body composition and mortality that leveraged diverse approaches to estimate body composition. Although studies showed inconsistent results, there was evidence suggesting that high fat mass and low lean body mass may be independently associated with mortality in the general population. This review may help partially explain the "obesity paradox" phenomenon and facilitate further studies to advance the understanding of the association of body composition on health in the general and patient populations.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.