ArticleClinical rehabilitation2019
Functional performance and safety of bone-anchored prostheses in persons with a transfemoral or transtibial amputation: a prospective one-year follow-up cohort study.
Article in Clinical rehabilitation, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06636136 (Transtibial Osseointegration Surgery Study), which is not on this map. Cited by 34 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Transtibial Osseointegration Surgery Study (TOSS)
Who cites it
34 citing papers in PubMed, 2 syntheses or guidelines pooled it, 62 citations in OpenAlex.
- Meta-analytic evaluation of complications and longevity of bone-anchored prostheses in lower extremity amputees: does design matter?Musculoskeletal surgery · 2026Pooled it
- Bone-anchored prostheses for transfemoral amputation: a systematic review of outcomes, complications, patient experiences, and cost-effectiveness.Frontiers in rehabilitation sciences · 2024Pooled it
- Trial
- Assessment and characterization of back pain and biopsychosocial influences in lower limb amputation: scoping review.Pain reports · 2026Review
- Tibial Bone-Anchored Prostheses: A Narrative Review of the Literature and Reflection on 10 Years of Surgical Practice.Annals of biomedical engineering · 2026Review
- A Preclinical Approach to 3D-Printed Osseointegration Prosthesis: Improving Functional Outcomes and Reducing Complications in Residual Limb Reconstruction.Annals of biomedical engineering · 2026Article
- Assessment of pain and functional outcomes after lower limb amputation: a scoping review.BMJ open · 2026Article
- CORR Insights®: How to Improve Patient Selection in Individuals With Lower Extremity Amputation Using a Bone-anchored Prosthesis.Clinical orthopaedics and related research · 2025Article
- How To Improve Patient Selection in Individuals With Lower Extremity Amputation Using a Bone-anchored Prosthesis.Clinical orthopaedics and related research · 2025Article
- Colorado Limb Donning-Timed Up and Go (COLD-TUG) Test in Lower-Extremity Amputation: Less Donning Time with Osseointegrated Bone-Anchored Prosthetic Limb.The Journal of bone and joint surgery. American volume · 2025Article
- Altered cumulative joint moments and increased joint moment symmetry during sit-to-stand transitions for transfemoral bone-anchored limb users: A case series.Clinical biomechanics (Bristol, Avon) · 2025Article
- Surgical technique of minor revision of a transcutaneous osseointegration prosthetic system (TOPS) with implant retention.Operative Orthopadie und Traumatologie · 2025Review
- Surgical technique of a transcutaneous osseointegration prosthesis system (TOPS) for transtibial amputees.Operative Orthopadie und Traumatologie · 2025Review
- Comparing the mechanical energetics of walking among individuals with unilateral transfemoral limb loss using socket and osseointegrated prosthetic interfaces.Scientific reports · 2025Article
- Lower Extremity Osseointegration Postoperative Rehabilitation Protocols: A Scoping Review.Physical therapy · 2025Article
- Cumulative loading increases and loading asymmetries persist during walking for people with a transfemoral bone-anchored limb.Gait & posture · 2024Article
- The nonsalvageable tibia: amputation and prosthetics.OTA international : the open access journal of orthopaedic trauma · 2024Review
- The biomechanical influence of transtibial Bone-Anchored limbs during walking.Journal of biomechanics · 2024Article
- Daily steps and stepping cadence increase one-year following prosthesis osseointegration in people with lower-limb amputation.Disability and rehabilitation · 2024Article
- Bone-anchored prostheses for lower limb amputation in a French cohort with 1-15 years of follow-up: implant survival rates, mechanical complications, and reported outcomes.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectives: (1) To compare level of function, activity, health-related quality of life (HRQoL) and satisfaction in persons with a lower extremity amputation before surgery and 6- and 12-months after implantation of an osseointegration implant and (2) to report adverse events.
design: Prospective cohort study.
setting: University medical centre. SUBJECTS:: A total of 40 consecutive persons (median age: 56 years) who received a transfemoral (31) or transtibial (9) osseointegration implant, between April 2014 and March 2016.
intervention: Osseointegration implant surgery followed by a predefined rehabilitation programme. MAIN MEASURES:: Hip abductor strength, prosthetic use, back pain frequency, postoperative pain, mobility level (Timed-Up and Go (TUG) and wheelchair-boundedness), walking ability (6 minute walking test (6MWT) and walking distance in daily life), HRQoL, satisfaction regarding the prosthesis, and adverse events.
results: Strength, prosthetic use, walking distance, HRQoL, and satisfaction level increased significantly at 6- and 12-month follow-up compared to baseline ( P ⩽ 0.002). The TUG showed no change at 6-month follow-up ( P = 0.420) but improved significantly at 12-month follow-up compared to baseline ( P = 0.005). Wheelchair-boundedness decreased from 12/40 participants at baseline to 0 at follow-ups. The 6MWT ( P ⩾ 0.038) and back pain ( P ⩾ 0.437) did not change over time. Stump pain was present in 28/39 and 22/40 of the participants at 6-and 12-month follow-up, respectively. The major adverse events were managed successfully and included three dual-cone breakages and four bone fractures. An uneventful course was completed by 19/31 transfemoral and 4/9 transtibial bone-anchored prostheses users.
conclusion: Bone-anchored prostheses lead to improved performance and appear to be safe, so they might be considered for persons with socket-related problems.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.