Evidence map›Paper›PMID 30537147›Full record

ArticleAlcoholism, clinical and experimental research2019

Role of ADHD in the Co-Occurrence Between Heavy Alcohol Use and Depression Trajectories in Adulthood.

Frances L Wang, Sarah L Pedersen, Heather Joseph, Elizabeth M Gnagy, Patrick Curran, William E Pelham, Brooke S G Molina

Open access · greenAbstract read
In one paragraph

Article in Alcoholism, clinical and experimental research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Frances L WangDepartment of Psychiatry, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania.ORCID 0000-0001-6548-0031
Sarah L PedersenDepartment of Psychiatry, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania.
Heather JosephDepartment of Psychiatry, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania.
Elizabeth M GnagyDepartment of Psychology, Florida International University, Miami, Florida.
Patrick CurranDepartment of Psychology, University of North Carolina, Chapel Hill, Chapel Hill, North Carolina.
William E PelhamDepartment of Psychology, Florida International University, Miami, Florida.
Brooke S G MolinaDepartment of Psychiatry, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania.
University of Pittsburgh Medical Center · USFlorida International University · USUniversity of North Carolina at Chapel Hill · US

Funding

CLINICAL RESEARCH TRAINING IN CHILD PSYCHIATRYT32MH018951 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI TINA R GOLDSTEIN · 1990 to 2026
$9.7M
DEVELOPMENT OF ALCOHOL USE AND ABUSE IN ADHD ADOLESCENTSR01AA011873 · NIAAA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MOLINA, BROOKE S.G. · 1998 to 2007
$8.5M
The Development of Alcohol Use and Abuse in ADHD Adolescents and Young AdultsR37AA011873 · NIAAA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MOLINA, BROOKE S.G. · 2008 to 2017
$7.9M
INTERDISCIPLINARY ALCOHOL RESEARCH TRAINING PROGRAMT32AA007453 · NIAAA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BROOKE S.G. MOLINA · 1985 to 2026
$3.7M
Neural correlates of adult outcomes of childhood ADHD: Affect, reward and controlR01MH101096 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI LADOUCEUR, CECILE D., MOLINA, BROOKE S.G. · 2014 to 2018
$3.0M
Development of Drug Use and Abuse in ADHD AdolescentsR01DA012414 · NIDA · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI PELHAM, WILLIAM E · 2001 to 2012
$2.2M
The Pittsburgh ADHD Longitudinal Study: Predicting alcohol misuse, problems, and disorder in mid-adulthoodR56AA011873 · NIAAA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MOLINA, BROOKE S.G. · 2018 to 2018
$100k
ADOLESCENT ALCOHOL ABUSE AND ATTENTION DEFICIT DISORDERK21AA000202 · NIAAA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MOLINA, BROOKE S.G. · 1995 to 1999
–
NIAAA NIH HHS K21 AA000202NIAAA NIH HHS R01 AA00202NIAAA NIH HHS R01 AA011873NIAAA NIH HHS R37 AA011873NIAAA NIH HHS R56 AA011873NIAAA NIH HHS T32 AA007453NIDA NIH HHS R01 DA012414NIMH NIH HHS R01 MH101096NIMH NIH HHS T32 MH018951
6 · The paper itself

Abstract

backgroundAttention-deficit/hyperactivity disorder (ADHD) is associated with greater heavy alcohol use and depressive symptoms in adulthood. Yet, few studies have investigated whether childhood ADHD predicts an increased association between heavy drinking and depression in adulthood when this co-occurrence becomes more common. We examined associations among heavy alcohol use and depression longitudinally from ages 21 to 29 and whether these associations differed for those with or without childhood ADHD, as well as for those with or without persistent ADHD in adulthood.

methodsData were from the Pittsburgh ADHD Longitudinal Study, a prospective cohort of children diagnosed with ADHD and demographically similar individuals without ADHD histories. ADHD symptoms in adulthood were self- and parent reported; depressive symptoms and frequency of drinking 5 or more drinks in a single drinking occasion were self-reported and measured at 5 time-points from ages 21 to 29. Depression and alcohol use were modeled in a multiple-group, parallel process longitudinal growth model.

resultsThe slopes of heavy alcohol use and depression were significantly and positively associated from ages 25 to 29 but not at the younger ages. Although the strength of these associations did not differ by group (with or without ADHD, childhood or adulthood), the slopes of depression and heavy drinking at the older ages were highly variable and individuals with ADHD showed significantly faster growth in depression from ages 25 to 29.

conclusionsDue to the strengthening association between heavy drinking and depression for adults in their late 20s, and increasing depression for adults with ADHD histories, individuals with ADHD may be at greater risk for co-occurring depression and binge drinking. Negative reinforcement-related alcohol use may strengthen as these individuals age toward the fourth decade of life. More rigorous testing of this possibility is warranted.

Indexed as

AdultAge FactorsAlcohol DrinkingAttention Deficit Disorder with HyperactivityCase-Control StudiesComorbidityDepressionFemaleHumansLongitudinal StudiesMalePennsylvaniaProspective StudiesYoung AdultADHDAdulthoodComorbidityDepressionHeavy Alcohol Use

Identifiers

PMID30537147
PMCPMC6370516
OpenAlexW2903930198

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.