Evidence map›Paper›PMID 30536963›Full record

ArticleHead & neck2019

Feasibility of indocyanine green fluorescence imaging for intraoperative identification of parathyroid glands during thyroid surgery.

Jacqueline van den Bos, Lottie van Kooten, Sanne M E Engelen, Tim Lubbers, Laurents P S Stassen, Nicole D Bouvy

Open access · hybridAbstract read
In one paragraph

Article in Head & neck, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 1 pooled it
5.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 1 synthesis or guideline pooled it, 61 citations in OpenAlex.

  1. Efficacy and role of indocyanine green angiography in thyroidectomy: a systematic review and meta-analysis.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025
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  14. The Utility of Near-Infrared Autofluorescence for Parathyroid Gland Identification During Thyroid Surgery: A Single-Center Experience.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Jacqueline van den BosDepartment of Surgery, Maastricht University Medical Center, Maastricht, The Netherlands.
Lottie van KootenFaculty of Health Medicine and Life Sciences, Maastricht University, Maastricht, The Netherlands.
Sanne M E EngelenDepartment of Surgery, Maastricht University Medical Center, Maastricht, The Netherlands.
Tim LubbersDepartment of Surgery, Maastricht University Medical Center, Maastricht, The Netherlands.
Laurents P S StassenDepartment of Surgery, Maastricht University Medical Center, Maastricht, The Netherlands.
Nicole D BouvyDepartment of Surgery, Maastricht University Medical Center, Maastricht, The Netherlands.
Maastricht University · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study assessed the feasibility of near-infrared fluorescence imaging with indocyanine green (ICG) to identify the parathyroid glands (PGs) intraoperatively and to assess their perfusion after thyroid resection.

methodsPatients undergoing elective thyroidectomy were enrolled in this prospective study. An intravenous bolus of 7.5 mg ICG was administered twice: the first bolus to identify the PGs before resection of the thyroid and the second to assess vascularization of the PGs after resection.

resultsA total of 30 operations in 26 patients were included. In 17 surgeries (56.7%), fluorescence imaging was of added value, especially to confirm the presence of a suspected PG. No intraoperative or postoperative complications occurred because of the use of ICG.

conclusionNear-infrared fluorescence imaging with the use of ICG for intraoperative identification of the PGs and the assessment of its vascularization is feasible and safe and can provide more certainty about the location of the PGs.

Indexed as

Coloring AgentsIndocyanine GreenOptical ImagingThyroidectomyAdultAgedFeasibility StudiesFemaleHumansIntraoperative CareMaleMiddle AgedParathyroid GlandsProspective StudiesThyroid DiseasesColoring AgentsIndocyanine Greenindocyanine greennear-infrared fluorescence imagingNIRFparathyroid glandthyroidectomy

Identifiers

PMID30536963
PMCPMC6590433
OpenAlexW2905288634

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.