ArticleJournal of anatomy2019
Melatonin release by exocytosis in the rat parotid gland.
Article in Journal of anatomy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
5 citing papers in PubMed, 8 citations in OpenAlex.
- Ameliorative effects of melatonin on radiotherapy-induced apoptotic and inflammatory responses in rat parotid gland.BMC oral health · 2026Article
- Prostate-specific antigen: An unfamiliar protein in the human salivary glands.Journal of anatomy · 2024Article
- Melatonin ultrastructural localization in mitochondria of human salivary glands.Journal of anatomy · 2023Article
- Brain-reactive autoantibodies in neuropsychiatric systemic lupus erythematosus.Frontiers in immunology · 2023Article
- Clinical significance of serum melatonin in predicting the severity of oral squamous cell carcinoma.Oncology letters · 2020Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Several beneficial effects on oral health are ascribed to melatonin. Due to its lipophilic nature, non-protein-bound circulating melatonin is usually thought to enter the saliva by passive diffusion through salivary acinar gland cells. Recently, however, using transmission electron microscopy (TEM), melatonin was found in acinar secretory granules of human salivary glands. To test the hypothesis that granular located melatonin is actively discharged into the saliva by exocytosis, i.e. contrary to the general belief, the β-adrenergic receptor agonist isoprenaline, which causes the degranulation of acinar parotid serous cells, was administered to anaesthetised rats. Sixty minutes after an intravenous bolus injection of isoprenaline (5 mg kg
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Registered trials
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