ArticleThe British journal of dermatology2019
Recurrence of periocular basal cell carcinoma and squamous cell carcinoma after Mohs micrographic surgery: a retrospective cohort study.
Article in The British journal of dermatology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 2 syntheses or guidelines pooled it, 53 citations in OpenAlex.
- Periorbital reconstructive techniques following Mohs micrographic surgery or excisions: a systematic review.Archives of dermatological research · 2023Pooled it
- Swiss Recommendations for Cutaneous Basal Cell Carcinoma.Dermatology (Basel, Switzerland) · 2023Guideline
- Vismodegib for Preservation of Visual Function in Patients with Advanced Periocular Basal Cell Carcinoma: The VISORB Trial.The oncologist · 2021Trial
- Cutaneous Adnexal Tumours in an Eastern European Cohort: Clinicopathological Spectrum and Rare Malignant Lesions.Cancers · 2026Article
- Surgical Outcomes and Histopathological Risk Factors in Periocular Basal Cell Carcinoma: A Single-Centre Study of 100 Patients.Turkish journal of ophthalmology · 2026Article
- Mohs Surgery vs. Wide Local Excision for Non-Melanoma Skin Cancer: Comparing Recurrence Rates, Economic Value, and Aesthetic Outcomes.Journal of cancer science and clinical therapeutics · 2026Article
- A 5-year retrospective review of post-Mohs reconstruction outcomes for periocular cutaneous malignancies at an academic medical center.Frontiers in ophthalmology · 2026Article
- A Systematic Review and Meta-Analysis of Ocular and Periocular Basal Cell Carcinoma with First-Time Description of Dermoscopic and Reflectance Confocal Microscopy Features of Caruncle Basal Cell Carcinoma.Diagnostics (Basel, Switzerland) · 2025Review
- Long-term results after surgical basal cell carcinoma excision in the eyelid region: revisited.Wiener klinische Wochenschrift · 2025Article
- Clinicopathologic Features of Eyelid Sebaceous Gland Carcinoma Requiring Immunohistochemical Diagnosis.Ocular oncology and pathology · 2024Article
- Review
- Results of Mohs' Micrographic Surgery of Periocular Basal Cell Carcinoma: The Swedish Experience.Acta dermato-venereologica · 2024Article
- Treatment of Basal Cell Carcinoma of the Lower Eyelid With High-Dose-Rate Brachytherapy.Cureus · 2024Article
- Line-Field Confocal Optical Coherence Tomography Evaluation of Eyelid Skin Lesions.Diagnostics (Basel, Switzerland) · 2023Article
- Surgical management of periocular squamous cell carcinoma: case report.Journal of medicine and life · 2023Article
- Mohs micrographic surgery for periocular skin cancer: a single-institution experience.Archives of dermatological research · 2023Article
- Periocular basal cell carcinoma recurrence following surgical treatment: Safe surveillance time.Eye (London, England) · 2023Article
- Paired-agent imaging as a rapidFrontiers in oncology · 2023Article
- Design and Validation of a Handheld Optical Polarization Imager for Preoperative Delineation of Basal Cell Carcinoma.Cancers · 2022Article
- Deep learning-based fully automated differential diagnosis of eyelid basal cell and sebaceous carcinoma using whole slide images.Quantitative imaging in medicine and surgery · 2022Article
Corrections and comments
- Commented on by
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDespite the widespread use of Mohs micrographic surgery (MMS) for periocular basal cell carcinoma (BCC) and squamous cell carcinoma (SCC) - together called keratinocyte carcinoma (KC) - follow-up data regarding recurrences are limited.
objectivesTo investigate the recurrence rate for periocular KCs after MMS and to describe our experience with interdisciplinary collaborations.
methodsPatients with periocular KCs treated with MMS between 2006 and 2016 in a tertiary MMS referral hospital were included in this retrospective cohort study. Descriptive statistics were used to describe the MMS procedure-related characteristics. Using follow-up data from the electronic patient records and linkage with the Dutch nationwide network and registry of histopathology and cytopathology on 30 June 2017, the recurrence rate was evaluated and calculated using a cumulative incidence curve.
resultsIn total, 683 (93·7%) periocular BCCs and 46 (6·3%) SCCs were treated with MMS. Three-quarters (n = 549) were primary tumours and the majority were located at the medial canthus or lower eyelid (n = 649, 89·0%). In 505 MMS procedures (69·3%) an oculoplastic surgeon participated, and in 63 patients (8·6%) a plastic surgeon performed the reconstruction. After a median follow-up of 46 months the recurrence rate was 3·0%, based on 22 recurrences (20 BCCs and two SCCs).
conclusionsMMS is an excellent treatment option for periocular KCs, with a low recurrence rate. Due to this specific anatomical location an interdisciplinary approach should pre-eminently be considered.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.