Evidence map›Paper›PMID 30536421›Full record

ReviewAnnals of neurology2019

Lyme Neuroborreliosis: Clinical Outcomes, Controversy, Pathogenesis, and Polymicrobial Infections.

Juan Carlos Garcia-Monco, Jorge L Benach

Abstract readReview
In one paragraph

Review in Annals of neurology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Tick-induced neurological disorders.Journal of neurology · 2025
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Review
  18. Article
  19. The case of a 38-year-old man with transient right arm weakness and dysarthria.Annals of clinical and translational neurology · 2024
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Juan Carlos Garcia-MoncoDepartment of Neurology, University Hospital of Basurto, Bilbao, Vizcaya, Spain.
Jorge L BenachDepartments of Molecular Genetics and Microbiology, Stony Brook University School of Medicine, Stony Brook, NY.

Funding

Antigen Specific Response to BorreliaR01AI027044 · NIAID · STATE UNIVERSITY NEW YORK STONY BROOK · PI BENACH, JORGE L. · 1989 to 2020
$3.7M
ANTIGEN SPECIFIC RESPONSES TO BORRELIAR37AI027044 · NIAID · STATE UNIVERSITY NEW YORK STONY BROOK · PI BENACH, JORGE L. · 1998 to 2007
$2.6M
Antigen Specific Responses to BorreliaR56AI027044 · NIAID · STATE UNIVERSITY NEW YORK STONY BROOK · PI BENACH, JORGE L. · 2015 to 2015
$467k
NIAID NIH HHS R01 AI027044NIAID NIH HHS R37 AI027044NIAID NIH HHS R56 AI027044NIH HHS AI027044
6 · The paper itself

Abstract

Lyme borreliosis is the object of numerous misconceptions. In this review, we revisit the fundamental manifestations of neuroborreliosis (meningitis, cranial neuritis, and radiculoneuritis), as these have withstood the test of time. We also discuss other manifestations that are less frequent. Stroke, as a manifestation of Lyme neuroborreliosis, is considered in the context of other infections. The summary of the literature regarding clinical outcomes of neuroborreliosis leads to its controversies. We also include new information on pathogenesis and on the polymicrobial nature of tick-borne diseases. In this way, we update the review that we wrote in this journal in 1995. ANN NEUROL 2019;85:21-31.

Indexed as

Borrelia burgdorferiCoinfectionHumansLyme DiseaseLyme NeuroborreliosisStrokeTreatment Outcome

Identifiers

PMID30536421
PMCPMC7025284

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.