Evidence map›Paper›PMID 30536223›Full record

Observational studyMusculoskeletal surgery2019

PEEK versus metal cages in posterior lumbar interbody fusion: a clinical and radiological comparative study.

F Cuzzocrea, A Ivone, E Jannelli, A Fioruzzi, E Ferranti, R Vanelli, F Benazzo

Registry-linked trialAbstract readComparative StudyObservational Study
PubMed Publisher
In one paragraph

Observational study in Musculoskeletal surgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05691062 (A Prospective, Randomized Comparison of Titanium vs. PEEK Fusion Devices in 1 Level TLIF), which is not on this map. Cited by 22 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05691062 phase4enrolling by invitationnot on this mapstarted 2024, after this paper: background citation

A Prospective, Randomized Comparison of Titanium vs. PEEK Fusion Devices in 1 Level TLIF

TypeinterventionalSponsorTwin Cities Spine CenterRan2024 to 2028Enrolled80ConditionsSpine Fusion, Lumbar Spondylolisthesis, Lumbar StenosisArmsTitanium Fusion Device, PEEK Fusion Device
3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Titanium (Ti) cages may be superior to polyetheretherketone (PEEK) cages in lumbar interbody fusion: a systematic review and meta-analysis of clinical and radiological outcomes of spinal interbody fusions using Ti versus PEEK cages.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2021
    Pooled it
  4. Speed and quality of interbody fusion in porous bioceramic AlJournal of orthopaedic surgery and research · 2023
    Trial
  5. A 7-year minimum follow-up of the M6-L total disk replacement for low back pain with radiculopathy in young railway employees: a retrospective single-center study.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
  6. Optimal cage biomaterials for fusion and subsidence outcomes in lumbar spinal fusion: a network meta-analysis of 4881 patients.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Observational
  18. Article
  19. Article
  20. Interbody Fusions in the Lumbar Spine: A Review.HSS journal : the musculoskeletal journal of Hospital for Special Surgery · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

F CuzzocreaS.C. Ortopedia e Traumatologia, IRCCS Policlinico San Matteo, Università degli Studi di Pavia, Viale Camillo Golgi 19, 27100, Pavia, PV, Italy.
A IvoneS.C. Ortopedia e Traumatologia, IRCCS Policlinico San Matteo, Università degli Studi di Pavia, Viale Camillo Golgi 19, 27100, Pavia, PV, Italy. alessandro.ivone87@gmail.com.ORCID http://orcid.org/0000-0003-0752-8978
E JannelliS.C. Ortopedia e Traumatologia, IRCCS Policlinico San Matteo, Università degli Studi di Pavia, Viale Camillo Golgi 19, 27100, Pavia, PV, Italy.
A FioruzziS.C. Ortopedia e Traumatologia, IRCCS Policlinico San Matteo, Università degli Studi di Pavia, Viale Camillo Golgi 19, 27100, Pavia, PV, Italy.
E FerrantiS.C. Ortopedia e Traumatologia, IRCCS Policlinico San Matteo, Università degli Studi di Pavia, Viale Camillo Golgi 19, 27100, Pavia, PV, Italy.
R VanelliS.C. Ortopedia e Traumatologia, IRCCS Policlinico San Matteo, Università degli Studi di Pavia, Viale Camillo Golgi 19, 27100, Pavia, PV, Italy.
F BenazzoS.C. Ortopedia e Traumatologia, IRCCS Policlinico San Matteo, Università degli Studi di Pavia, Viale Camillo Golgi 19, 27100, Pavia, PV, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLow back pain and sciatica represent a common disabling condition with a significant impact on the social, working and economic lives of patients. Transforaminal lumbar interbody fusion (TLIF) is a surgical procedure used in degenerative spine conditions. Several types of cages were used in the TLIF procedure. PURPOSE: To determine whether there is a difference in terms of symptomatology improvement, return to daily activities and fusion rate between metal cages and polyetheretherketone (PEEK) cages.

methodsWe have retrospectively reviewed 40 patients who have undergone TLIF from October 2015 to May 2016. All patients were clinically evaluated with questionnaires and were assessed with CT scan and standing X-ray films of the full-length spine.

resultsWe found no significant functional differences in the two groups. At 1-year follow-up, osteolysis was present in 50% of cases of the PEEK cages and in 10% cases of the metal cages. The degree of fusion at 1  year was evaluated as complete in 40% cases of the metal cages and 15% cases of the PEEK cages.

conclusionsWe have found a better fusion rate and prevalence of fusion in the group treated with metal cages, reflecting the well-known osteoinductive properties of titanium and tantalum.

Indexed as

Activities of Daily LivingAdultBenzophenonesBiocompatible MaterialsFemaleHumansKetonesLow Back PainLumbar VertebraeMaleMiddle AgedOsteolysisPain MeasurementPolyethylene GlycolsPolymersRetrospective StudiesBenzophenonesBiocompatible MaterialsKetonespolyetheretherketonePolyethylene GlycolsPolymersTantalumTitaniumCagePEEKTantalumTitaniumTLIF

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.