Evidence map›Paper›PMID 30536170›Full record

ArticleExperientia supplementum (2012)

Inflammasome in the Pathogenesis of Pulmonary Diseases.

Fengying Xu, Zongmei Wen, Xueying Shi, Jie Fan

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Experientia supplementum (2012). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Advances in laboratory medicine · 2020
    Review
  5. Advances in laboratory medicine · 2020
    Review
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 2 countries.

Fengying XuDepartment of Anesthesiology, No. 401 Hospital, Qingdao, China.
Zongmei WenDepartment of Anesthesiology, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China.
Xueying ShiDepartment of Anesthesiology and Critical Care, Shanghai Xinghua Hospital, Jiaotong University School of Medicine, Shanghai, China.
Jie FanDepartment of Surgery, University of Pittsburgh School of Medicine, Pittsburgh, USA. jif7@pitt.edu.
People's Liberation Army 401 Hospital · CNTongji University · CNUniversity of Pittsburgh · USXinHua Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lung diseases are common and significant causes of illness and death around the world. Inflammasomes have emerged as an important regulator of lung diseases. The important role of IL-1 beta and IL-18 in the inflammatory response of many lung diseases has been elucidated. The cleavage to turn IL-1 beta and IL-18 from their precursors into the active forms is tightly regulated by inflammasomes. In this chapter, we structurally review current evidence of inflammasome-related components in the pathogenesis of acute and chronic lung diseases, focusing on the "inflammasome-caspase-1-IL-1 beta/IL-18" axis.

Indexed as

InflammasomesCaspase 1HumansInterleukin-18Interleukin-1betaLung DiseasesCaspase 1IL1B protein, humanInflammasomesInterleukin-18Interleukin-1betaChronic obstructive pulmonary diseaseInfectious pulmonary diseasesInflammasomesLung injurySmoking

Identifiers

PMID30536170
PMCPMC7123416
OpenAlexW2891305783

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.