Evidence map›Paper›PMID 30536115›Full record

ArticleInternational journal of colorectal disease2019

Does enhanced recovery improve the survival rates of patients 3 years after undergoing surgery to remove a tumor in the colon?

P Viannay, A Hamy, R Jaouen, F X Caroli-Bosc, C Luel, S Vasseur, M Levaillant, J F Hamel, Aurélien Venara

Abstract read
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In one paragraph

Article in International journal of colorectal disease, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  3. Article
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

P ViannayDepartment of Visceral and Endocrinal Surgery, CHU Angers, 4 rue Larrey, 49933, Angers Cedex 9, France.
A HamyDepartment of Visceral and Endocrinal Surgery, CHU Angers, 4 rue Larrey, 49933, Angers Cedex 9, France.
R JaouenDepartment of Visceral and Endocrinal Surgery, CHU Angers, 4 rue Larrey, 49933, Angers Cedex 9, France.
F X Caroli-BoscDépartement de Médecine, UFR Santé d'Angers, Angers, France.
C LuelDépartement de Médecine, UFR Santé d'Angers, Angers, France.
S VasseurDépartement de Médecine, UFR Santé d'Angers, Angers, France.
M LevaillantDepartment of Biostatistics, CHU Angers, 4 rue Larrey, 49933, Angers Cedex 9, France.
J F HamelDépartement de Médecine, UFR Santé d'Angers, Angers, France.
Aurélien VenaraDepartment of Visceral and Endocrinal Surgery, CHU Angers, 4 rue Larrey, 49933, Angers Cedex 9, France. auvenara@yahoo.fr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe advantages of enhanced recovery programs (ERP) after colorectal surgery for morbidity and length of stay are well known. On a longer term, evidence is much more limited. The aim of this study is to determine the impact of ERP on survival after 3 years of follow-up, following colorectal cancer surgery.

methodsAll the patients undergoing resection for colorectal cancer between the years 2010 and 2014 were included. Patients were classified according to their compliance with the ERP (< 70 or ≥ 70%).

resultsAmong the 206 patients included during the period, 129 were male (62.6%). The 3-year overall survival rate was 70.4% (145 patients) and relapse-free survival was 59.2% (122 patients). The survival after 3 years was influenced by the initial metastatic status (p < 0.0001), operative morbidity (p < 0.001), and the presence of peritumoral emboli (p = 0.006). However, the compliance with the ERP ≥ 70% did not influence overall survival (p = 0.63), nor relapse-free survival (p = 0.93). The same observations were found among the "at-risk" population (synchronous metastasis and postoperative complication).

conclusionThe ERP does not seem to influence the 3-year relapse-free survival after colorectal resection for cancer.

Indexed as

AgedColonColorectal NeoplasmsFemaleHumansMaleNeoplasm MetastasisPatient CompliancePostoperative ComplicationsRecurrenceRisk FactorsSurvival RateColorectal cancerDisease-free survivalEnhanced recoveryGlobal survival

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.