ArticleClinical research in cardiology : official journal of the German Cardiac Society2019
Left atrial strain improves estimation of filling pressures in heart failure: a simultaneous echocardiographic and invasive haemodynamic study.
Article in Clinical research in cardiology : official journal of the German Cardiac Society, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
44 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Prognostic value of left atrial strain in acute and chronic heart failure: A meta-analysis.ESC heart failure · 2025Pooled it
- Left atrial structure and function in heart failure with reduced (HFrEF) versus preserved ejection fraction (HFpEF): systematic review and meta-analysis.Heart failure reviews · 2022Pooled it
- Diagnostic value of echocardiographic markers for diastolic dysfunction and heart failure with preserved ejection fraction.Heart failure reviews · 2022Pooled it
- Meta-analysis of echocardiographic quantification of left ventricular filling pressure.ESC heart failure · 2021Pooled it
- Left Atrial Reservoir Strain and Heart Failure Rehospitalization Burden in Acute Heart Failure With Atrial Fibrillation.Echocardiography (Mount Kisco, N.Y.) · 2026Article
- Development of a Diagnostic Model Based on Serum ST2 and Left Atrial Strain for Left Ventricular Systolic Dysfunction in Patients With Chronic Coronary Syndrome.Echocardiography (Mount Kisco, N.Y.) · 2026Article
- Applications of Left Atrial Strain in Cardiovascular Disease: A Comprehensive Review of Recent Evidence.Reviews in cardiovascular medicine · 2026Review
- Cardiovascular magnetic resonance-derived left atrial parameters for assessing diastolic dysfunction and prognosis in hypertrophic cardiomyopathy.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2026Article
- Calibrated Integrated Backscatter Is Associated With Increased Left Ventricular Concentricity and Left Atrial Stiffness in Resistance Trained Individuals Using Anabolic-Androgenic Steroids.Echocardiography (Mount Kisco, N.Y.) · 2026Article
- Screening for HFpEF in pacemaker patients: Study design and protocol of the PM-HFpEF study.PloS one · 2026Article
- Left Atrial Reservoir Strain in Cardiovascular and Systemic Disease: Advances and Clinical Applications From Physiology to Practice.Reviews in cardiovascular medicine · 2025Review
- Left atrial reservoir strain as a predictor for left ventricular filling pressure in patients with sinus rhythm.Scientific reports · 2025Article
- Left Atrial Strain-Current Review of Clinical Applications.Diagnostics (Basel, Switzerland) · 2025Review
- Correlation of left atrial strain with invasively measured left ventricular end-diastolic pressure; determining LA strain cut-off value.The international journal of cardiovascular imaging · 2024Article
- Interpreting Diastolic Dynamics and Evaluation through Echocardiography.Life (Basel, Switzerland) · 2024Review
- Prognostic value of temporal patterns of left atrial reservoir strain in patients with heart failure with reduced ejection fraction.Clinical research in cardiology : official journal of the German Cardiac Society · 2024Observational
- Current and Clinically Relevant Echocardiographic Parameters to Analyze Left Atrial Function.Journal of cardiovascular development and disease · 2024Review
- Evolving Applications of Echocardiography in the Evaluation of Left Atrial and Right Ventricular Strain.Current cardiology reports · 2024Review
- Left ventricular and atrial myocardial strain in heart failure with preserved ejection fraction: the evidence so far and prospects for phenotyping strategy.Cardiovascular ultrasound · 2024Review
- The impact of image and performance enhancing drugs on atrial structure and function in resistance trained individuals.Echo research and practice · 2023Article
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
aimsLeft ventricular diastolic pressure estimation is essential for characterization of heart failure (HF). Patients with normal resting left atrial (LA) pressures (LAP), but steep LAP elevation on exertion, pose a particular diagnostic challenge. Current recommendations on echocardiographic LAP estimation have limited accuracy. Our aim was to investigate whether LA mechanical alterations assessed by LA strain (LA-GS) can contribute to non-invasive LAP diagnostics. METHODS AND
resultsSimultaneous echocardiographic and right heart catheterization (RHC) data at rest and during exercise was analyzed in 164 prospectively enrolled patients, referred for RHC due to HF symptoms. 56% had preserved ejection fraction (pEF). At rest, 97 patients displayed elevated mean pulmonary arterial wedge pressure (PAWP
conclusionLA-GS comprises a robust method for PAWP
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Registered trials
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