Evidence map›Paper›PMID 30535930›Full record

ReviewDrugs & aging2019

Approaches to Deprescribing Psychotropic Medications for Changed Behaviours in Long-Term Care Residents Living with Dementia.

Stephanie L Harrison, Monica Cations, Tiffany Jessop, Sarah N Hilmer, Mouna Sawan, Henry Brodaty

Registry-linked trialAbstract readReview
PubMed Publisher
In one paragraph

Review in Drugs & aging, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06273917 (Deprescribing Potentially Inappropriate Medications in the Emergency Department for Persons Living With Dementia), which is not on this map. Cited by 23 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 2 pooled it
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06273917 nacompletednot on this mapstarted 2024, after this paper: background citation

Deprescribing Potentially Inappropriate Medications in the Emergency Department for Persons Living With Dementia

TypeinterventionalSponsorNational Institute on Aging (NIA)Ran2024 to 2025Enrolled300ConditionsDementiaArmsPRIDE
3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 2 syntheses or guidelines pooled it, 65 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Drug-Drug Interactions in Nursing Home Residents With vs Without Dementia.Journal of the American Medical Directors Association · 2026
    Observational
  6. Article
  7. Article
  8. Observational
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Review
  19. Prevalence and Associated Factors of Polypharmacy in Nursing Home Residents: A Cross-Sectional Study.International journal of environmental research and public health · 2021
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Stephanie L HarrisonRegistry of Older South Australians, South Australian Health and Medical Research Institute (SAHMRI), PO Box 11060, Adelaide, SA, Australia. stephanie.harrison@sa.gov.au.
Monica CationsNHMRC Cognitive Decline Partnership Centre, The University of Sydney, Sydney, NSW, Australia.ORCID 0000-0002-9262-0463
Tiffany JessopDementia Centre for Research Collaboration, School of Psychiatry, UNSW Sydney, Sydney, NSW, Australia.
Sarah N HilmerNHMRC Cognitive Decline Partnership Centre, The University of Sydney, Sydney, NSW, Australia.
Mouna SawanNHMRC Cognitive Decline Partnership Centre, The University of Sydney, Sydney, NSW, Australia.
Henry BrodatyDementia Centre for Research Collaboration, School of Psychiatry, UNSW Sydney, Sydney, NSW, Australia.
The University of Sydney · AUUNSW Sydney · AUFlinders Medical Centre · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Psychotropic medications have a high risk of serious adverse events and small effect size for changed behaviours for people with dementia. Non-pharmacological approaches are recommended as first-line treatment for changed behaviours, yet psychotropic medications remain highly prevalent in long-term aged care settings. This narrative review describes the current evidence regarding deprescribing psychotropic medications for people with dementia in long-term care. Deprescribing psychotropic medications can be achieved without harm to the person with dementia, and most people experience no withdrawal symptoms. Interventions to deprescribe psychotropic medications should be multifactorial, including lowering the dose of the medication over time, educational interventions and psychological support. However, implementing this is a significant challenge due to the overreliance on psychotropic medications for behavioural management in long-term aged care. Facilitators to deprescribing psychotropic medications in long-term care include multidisciplinary teams with adequate training, education and managerial support, engaging residents and families and change 'champions'. Deprescribing practices should be person-centred, and an individualised deprescribing protocol should be in place, followed by careful monitoring of the individual. The person with dementia and their family, general practitioner, pharmacist, and allied health and direct care staff should all be involved throughout the deprescribing process. Direct care staff need adequate support, education and training, so they can effectively help the individual and implement person-centred approaches in the absence of psychotropic medications. Effective communication between residents and staff and amongst staff is consistently shown to be an important factor for deciding whether deprescribing of a medication should occur and the successful implementation of deprescribing psychotropic medications.

Indexed as

DeprescriptionsAgedAge FactorsBehaviorDementiaGeneral PractitionersHumansLong-Term CarePsychotropic DrugsPsychotropic Drugs

Identifiers

PMID30535930
OpenAlexW2905213524

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.