ReviewDrugs & aging2019
Approaches to Deprescribing Psychotropic Medications for Changed Behaviours in Long-Term Care Residents Living with Dementia.
Review in Drugs & aging, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06273917 (Deprescribing Potentially Inappropriate Medications in the Emergency Department for Persons Living With Dementia), which is not on this map. Cited by 23 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Deprescribing Potentially Inappropriate Medications in the Emergency Department for Persons Living With Dementia
Who cites it
23 citing papers in PubMed, 2 syntheses or guidelines pooled it, 65 citations in OpenAlex.
- Medicine Optimisation and Deprescribing Intervention Outcomes for Older People with Dementia or Mild Cognitive Impairment: A Systematic Review.Drugs & aging · 2025Pooled it
- What Makes Deprescription of Psychotropic Drugs in Nursing Home Residents with Dementia so Challenging? A Qualitative Systematic Review of Barriers and Facilitators.Drugs & aging · 2021Pooled it
- Tailoring a complex intervention to reduce antidepressants in institutionalized older persons with dementia.BMC health services research · 2022Trial
- The effect of educational intervention on use of psychotropics in defined daily doses and related costs - a randomized controlled trial.Scandinavian journal of primary health care · 2022Trial
- Drug-Drug Interactions in Nursing Home Residents With vs Without Dementia.Journal of the American Medical Directors Association · 2026Observational
- Psychotropic medications versus non-pharmacologic approaches for managing behavioural and psychological symptoms in Australian aged care residents with dementia: general practitioners' and physicians' perspectives.Therapeutic advances in psychopharmacology · 2025Article
- Factors associated with eating performance in nursing home residents living with dementia and other comorbidities.BMC geriatrics · 2024Article
- Clinical impact of an individualised clinical pharmacy programme into the memory care pathway of older people: an observational study.International journal of clinical pharmacy · 2024Observational
- Article
- Young-onset dementia diagnosis, management and care: a narrative review.The Medical journal of Australia · 2023Review
- Article
- Psychotropic medication deprescribing in residential aged care facilities: An exploratory study of the knowledge and attitudes of family members of residents with dementia.Australasian journal on ageing · 2022Article
- Enhancing deprescribing: A qualitative understanding of the complexities of pharmacist-led deprescribing in care homes.Health & social care in the community · 2022Article
- Attitudes toward deprescribing among older adults with dementia in the United States.Journal of the American Geriatrics Society · 2022Article
- As-Needed Prescribing and Administration of Psychotropic Medications in Assisted Living: A 7-State Study.Journal of the American Medical Directors Association · 2022Article
- Trauma-informed care in geriatric inpatient units to improve staff skills and reduce patient distress: a co-designed study protocol.BMC geriatrics · 2021Article
- Interventions to optimize medication use in nursing homes: a narrative review.European geriatric medicine · 2021Review
- Depression, antidepressants and fall risk: therapeutic dilemmas-a clinical review.European geriatric medicine · 2021Review
- Prevalence and Associated Factors of Polypharmacy in Nursing Home Residents: A Cross-Sectional Study.International journal of environmental research and public health · 2021Article
- Syndrome-Based Prescription to Optimize Psychotropics: Are CHROME Criteria a Game Changer?Frontiers in psychiatry · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Psychotropic medications have a high risk of serious adverse events and small effect size for changed behaviours for people with dementia. Non-pharmacological approaches are recommended as first-line treatment for changed behaviours, yet psychotropic medications remain highly prevalent in long-term aged care settings. This narrative review describes the current evidence regarding deprescribing psychotropic medications for people with dementia in long-term care. Deprescribing psychotropic medications can be achieved without harm to the person with dementia, and most people experience no withdrawal symptoms. Interventions to deprescribe psychotropic medications should be multifactorial, including lowering the dose of the medication over time, educational interventions and psychological support. However, implementing this is a significant challenge due to the overreliance on psychotropic medications for behavioural management in long-term aged care. Facilitators to deprescribing psychotropic medications in long-term care include multidisciplinary teams with adequate training, education and managerial support, engaging residents and families and change 'champions'. Deprescribing practices should be person-centred, and an individualised deprescribing protocol should be in place, followed by careful monitoring of the individual. The person with dementia and their family, general practitioner, pharmacist, and allied health and direct care staff should all be involved throughout the deprescribing process. Direct care staff need adequate support, education and training, so they can effectively help the individual and implement person-centred approaches in the absence of psychotropic medications. Effective communication between residents and staff and amongst staff is consistently shown to be an important factor for deciding whether deprescribing of a medication should occur and the successful implementation of deprescribing psychotropic medications.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.