Trial reportMolecular imaging and biology2019
Quantification of Positron Emission Tomography Data Using Simultaneous Estimation of the Input Function: Validation with Venous Blood and Replication of Clinical Studies.
Trial report in Molecular imaging and biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Non-invasive kinetic modelling approaches for quantitative analysis of brain PET studies.European journal of nuclear medicine and molecular imaging · 2023Pooled it
- Serotonin 1A Receptor Binding of [11C]CUMI-101 in Bipolar Depression Quantified Using Positron Emission Tomography: Relationship to Psychopathology and Antidepressant Response.The international journal of neuropsychopharmacology · 2022Trial
- Prediction of lithium treatment response in bipolar depression using 5-HTT and 5-HTEuropean journal of nuclear medicine and molecular imaging · 2020Trial
- Advances and Challenges in Pharmacokinetic Modeling for PET Imaging: Compartment Models, Input Functions, and Quantitative Techniques.Tomography (Ann Arbor, Mich.) · 2026Review
- A robust and versatile deep learning model for prediction of the arterial input function in dynamic small animal [EJNMMI research · 2026Article
- Variability of the arterial input function in small-animal dynamic PET imaging.EJNMMI research · 2026Article
- Optimization-derived blood input function using a kernel method and its evaluation with total-body PET for brain parametric imaging.NeuroImage · 2024Article
- Simultaneous estimation of a model-derived input function for quantifying cerebral glucose metabolism with [EJNMMI physics · 2024Article
- Deep-learning-derived input function in dynamic [Frontiers in nuclear medicine · 2024Article
- A convolutional neural network-based system to estimate the arterial plasma radioactivity curve in 18 F-FDG dynamic brain PET study.Nuclear medicine communications · 2023Article
- Article
- Development of a minimally invasive simultaneous estimation method for quantifying translocator protein binding with [EJNMMI research · 2023Article
- Article
- Brain 5-HT1A Receptor PET Binding, Cortisol Responses to Stress, and the Familial Transmission of Suicidal Behavior.The international journal of neuropsychopharmacology · 2022Article
- NRM 2021 Abstract Booklet.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2021Article
- Cerebral blood flow measurements withJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2021Article
- Examining the underpinnings of loudness dependence of auditory evoked potentials with positron emission tomography.NeuroImage · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
Abstract
purposeTo determine if one venous blood sample can substitute full arterial sampling in quantitative modeling for multiple positron emission tomography (PET) radiotracers using simultaneous estimation of the input function (SIME). PROCEDURES: Participants underwent PET imaging with [
resultsVenous and arterial metabolite-corrected plasma activities were within 6 % of each other at varying time points. vSIME- and AIF-derived outcome measures were in good agreement, with optimal sampling times of 12 min ([
conclusionsWe demonstrate the feasibility of AIF recovery using SIME with one venous sample for [
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Registered trials
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