Evidence map›Paper›PMID 30535666›Full record

Observational studyTechniques in coloproctology2018

Anal Fistula Laser Closure: the length of fistula is the Achilles' heel.

A Lauretta, N Falco, E Stocco, R Bellomo, A Infantino

Registry-linked trialAbstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in Techniques in coloproctology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07452666 (FISTULA-RFA Trial), which is not on this map. Cited by 32 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07452666 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

FISTULA-RFA Trial (Fistula Inactivation by Segmental Thermal Uniform Lesion Ablation-Radiofrequency Ablation): A Prospective, Multicenter, Single-Arm Pilot Study in Patients With Perianal Fistula

TypeinterventionalSponsorKorea University Ansan HospitalRan2026 to 2027Enrolled80ConditionsRectal FistulasArmsRadiofrequency Ablation (RFA) for Perianal Fistula
3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 4 syntheses or guidelines pooled it.

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  7. Core-Out Fistulectomy Combined With Laser Ablation of the Trans-Sphincteric Fistula Tract: A Pilot Study of Efficacy and Safety.Medical science monitor : international medical journal of experimental and clinical research · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

A LaurettaChirurgia Oncologica Generale, Centro di Riferimento Oncologico di Aviano (CRO), IRCCS, Aviano, 33081, Italy. andrea.lauretta@cro.it.
N FalcoDepartment of Surgery, AAS-5 Friuli Venezia Giulia (affiliation with University of Palermo), San Vito al Tagliamento, 33078, Italy.
E StoccoDepartment of Surgery, ASS-5 Friuli Venezia Giulia, San Vito al Tagliamento, 33078, Italy.
R BellomoDepartment of Surgery, ASS-5 Friuli Venezia Giulia, San Vito al Tagliamento, 33078, Italy.
A InfantinoDepartment of Surgery, ASS-5 Friuli Venezia Giulia, San Vito al Tagliamento, 33078, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLaser closure is a novel sphincter-saving technique for the treatment of anal fistula. The aim of this study was to report middle term results of laser treatment without closure of the internal orifice and to identify prognostic factors to improve selection criteria and maximize healing.

methodsA retrospective observational study was conducted on patients treated with laser for transphinteric anal fistula. A diode laser emitting laser energy of 12W at a wavelength of 1470 nm was used. The relationship between fistula healing and age, sex, previous fistula surgery, location of fistula, and length of fistula tract was investigated. A successful outcome was defined by the complete healing of the surgical wound and external opening for at least 6 months.

resultsThirty patients (16 males, median age 52 years, range 26-72 years) underwent laser fistula closure between January 2015 and December 2016. Cure was achieved in 10 patients (33.3%). The mean follow-up was 11.30 months (range 6-24 months). Patients with persistent or recurrent fistula were offered repeat surgery. Eventually 4 underwent laser treatment once more. Two patients were cured leading to an overall healing rate of 40% (12 out of 30). Only 4 minor complications occurred (13.3%). No worsening of anal continence was registered. Only fistula length had a statistically significant correlation with successful treatment. Fistula tracts shorter than 30 mm were associated with a primary healing rate of 58.3% while tracts longer than 30 mm were cured in only 16.6% of cases (p < 0.02).

conclusionsLaser closure is a safe and effective treatment for transphinteric anal fistula. The fistula length is the only significant prognostic factor when closing anal fistulas exclusively with laser: shorter fistulas have a better outcome.

Indexed as

AdultAgedAnal CanalFemaleHumansLasers, SemiconductorMaleMiddle AgedPatient SelectionPrognosisRectal FistulaRecurrenceRetrospective StudiesTreatment OutcomeWound HealingAnal fistulaLaserPrognostic factorsSphincter-saving technique

Identifiers

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.