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ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2019

Body Mass Index, waist circumference, and health-related quality of life in adults with chronic kidney disease.

Young Youl Hyun, Kyu-Beck Lee, Wookyung Chung, Yong-Soo Kim, Seung Hyeok Han, Yun Kyu Oh, Dong-Wan Chae, Sue Kyung Park, Kook-Hwan Oh, Curie Ahn and 1 more

Abstract readMulticenter Study
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In one paragraph

Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Young Youl HyunDivision of Nephrology, Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, 29 Saemunan-ro, Jongno-gu, Seoul, 03181, Korea.
Kyu-Beck LeeDivision of Nephrology, Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, 29 Saemunan-ro, Jongno-gu, Seoul, 03181, Korea. kyubeck.lee@samsung.com.ORCID http://orcid.org/0000-0002-3904-5404
Wookyung ChungDepartment of Internal Medicine, Gil Hospital, Gachon University, Inchon, Korea.
Yong-Soo KimDepartment of Internal Medicine, College of Medicine, Seoul St. Mary's Hospital, The Catholic University of Korea, Seoul, Korea.
Seung Hyeok HanDepartment of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.
Yun Kyu OhDepartment of Internal Medicine, Seoul National University Boramae Medical Center, Seoul, Korea.
Dong-Wan ChaeDepartment of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.
Sue Kyung ParkDepartment of Preventive Medicine, College of Medicine, Seoul National University Hospital, Seoul National University, Seoul, Korea.
Kook-Hwan OhDepartment of Internal Medicine, College of Medicine, Seoul National University Hospital, Seoul National University, Seoul, Korea.
Curie AhnDepartment of Internal Medicine, College of Medicine, Seoul National University Hospital, Seoul National University, Seoul, Korea.
KNOW-CKD Study Investigator

Funding

Korea Centers for Disease Control & Prevention 2011E3300300Korea Centers for Disease Control & Prevention 2012E3301100Korea Centers for Disease Control & Prevention 2013E3301600
6 · The paper itself

Abstract

purposeObesity is linked to poor health-related quality of life (HRQOL) in the general population, but its role in chronic kidney disease (CKD) is uncertain.

methodsWe conducted a cross-sectional study that investigated 1880 participants from the KoreaN cohort study for Outcome in patients With CKD (KNOW-CKD) who underwent complete baseline laboratory tests, health questionnaires, and HRQOL. HRQOL was assessed by physical component summary (PCS) and mental component summary (MCS) of the SF-36 questionnaire. We used multivariable linear regression models to examine the relationship between Body Mass Index (BMI) and sex-specific waist circumference (WC) with HRQOL.

resultsAdults with higher BMI and greater WC showed lower PCS. After adjusting for age, sex, socioeconomic state, comorbidities, and laboratory findings, we found that WC, but not BMI, was associated with PCS. Greater WC quintiles were associated with lower PCS [WC-4th quintile (β, - 2.63, 95% CI - 5.19 to - 0.06) and WC-5th quintile (β, - 3.71, 95% CI - 6.28 to - 1.15)]. The association between WC and PCS was more pronounced in older adults, woman, patients with diabetes, cardiovascular disease, or lower eGFR. The relationship between BMI and WC with MCS was not significant.

conclusionsIn adults with CKD, WC is a better indicator of poor physical HRQOL than BMI. The association between WC and physical HRQOL is modified by age, sex, eGFR, and comorbidities such as diabetes and cardiovascular disease.

Indexed as

Body Mass IndexAdultAgedCross-Sectional StudiesFemaleHumansMaleMiddle AgedProspective StudiesQuality of LifeRenal Insufficiency, ChronicWaist CircumferenceYoung AdultBMICKDHRQOLWaist circumference

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.