Evidence map›Paper›PMID 30535266›Full record

ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2019

Detection of Cryptococcus DNA by Metagenomic Next-generation Sequencing in Symptomatic Cryptococcal Antigenemia.

Prashanth S Ramachandran, Fiona V Cresswell, David B Meya, Charles Langelier, Emily D Crawford, Joseph L DeRisi, David R Boulware, Michael R Wilson

Open access · bronzeAbstract readLetterComment
In one paragraph

Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 17 citations in OpenAlex.

  1. Trial
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  4. Infection and drug resistance · 2023
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Prashanth S RamachandranDepartment of Neurology, University of California at San Francisco.
Fiona V CresswellInfectious Diseases Institute, Makerere University, Kampala, Uganda.
David B MeyaInfectious Diseases Institute, Makerere University, Kampala, Uganda.
Charles LangelierDivision of Infectious Diseases, Department of Medicine, University of California, San Francisco.
Emily D CrawfordChan Zuckerberg Biohub, University of California at San Francisco.
Joseph L DeRisiChan Zuckerberg Biohub, University of California at San Francisco.
David R BoulwareDepartment of Medicine, University of Minnesota, Minneapolis.
Michael R WilsonDepartment of Neurology, University of California at San Francisco.
Chan Zuckerberg Initiative (United States) · USMakerere University · UGUniversity of California, San Francisco · USUniversity of Minnesota · US

Funding

Improving Diagnostics and Neurocognitive Outcomes in HIV/AIDS-related MeningitisR01NS086312 · NINDS · UNIVERSITY OF MINNESOTA · PI David R Boulware, David Bisagaya Meya · 2013 to 2026
$8.3M
Northern/Pacific Universities Global Health Research Training ConsortiumR25TW009345 · FIC · UNIVERSITY OF WASHINGTON · PI KOLARS, JOSEPH C., NERURKAR, VIVEK RAMCHANDRA · 2012 to 2016
$5.9M
Redefining Tuberculosis Meningitis with Metagenomics and Host TransciptomicsR01AI145437 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI WILSON, MICHAEL R · 2019 to 2023
$3.5M
Operational Research for Cryptococcal Antigen Screening (ORCAS) of HIV PatientsU01AI125003 · NIAID · UNIVERSITY OF MINNESOTA · PI BOULWARE, DAVID R, MEYA, DAVID BISAGAYA · 2016 to 2020
$3.4M
Next-Generation Diagnostics for Acute EncephalitisK08NS096117 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI WILSON, MICHAEL R · 2017 to 2021
$999k
Profiling the Lung Transcriptome for Precision Diagnosis of Respiratory Infections using Host/Pathogen Metagenomic SequencingK23HL138461 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI LANGELIER, CHARLES · 2018 to 2021
$718k
FIC NIH HHS R25 TW009345NHLBI NIH HHS K23 HL138461NIAID NIH HHS R01 AI145437NIAID NIH HHS U01 AI125003NINDS NIH HHS K08 NS096117NINDS NIH HHS R01 NS086312Wellcome Trust 107742/Z/15/ZWellcome Trust M007413/1
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

CryptococcusMeningitis, CryptococcalCD4 Lymphocyte CountDNAHigh-Throughput Nucleotide SequencingHumansDNAcryptococcal antigenemiaHIVmeningitismetagenomic next-generation sequencing

Identifiers

PMID30535266
PMCPMC6784254
OpenAlexW2904708068

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.