ArticleEuropean journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery2019
Cardiac remodelling following thoracic endovascular aortic repair for descending aortic aneurysms.
Article in European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02735720 (The CardiOvascular Remodeling Following Endovascular Aortic Repair), which is not on this map. Cited by 30 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The CardiOvascular Remodeling Following Endovascular Aortic Repair (CORE) Study
Who cites it
30 citing papers in PubMed, 2 syntheses or guidelines pooled it, 100 citations in OpenAlex.
- Left ventricular remodeling and modification of aortic stiffness after endovascular aortic repair: a systematic review and meta-analysis.Langenbeck's archives of surgery · 2026Pooled it
- Endovascular versus conventional open surgical repair for thoracoabdominal aortic aneurysms.The Cochrane database of systematic reviews · 2022Pooled it
- Changes in aortic centerline length and curvature predict aortic diameter growth in chronic type B aortic dissection.JTCVS open · 2026Article
- Evaluation of Blood Flow Energy Loss before and after Endovascular Aneurysm Repair Using Four-dimensional Flow MR Imaging.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2026Article
- Windkessel Preserving Aortic Stent Graft Attenuates Left Ventricular Remodelling after Thoracic Endovascular Aortic Repair in a Porcine Model.European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery · 2026Article
- Investigating the role of structural wall stress in aortic growth prognosis in acute uncomplicated type B aortic dissection.Biomechanics and modeling in mechanobiology · 2025Article
- Deployment of a digital twin using the coupled momentum method for fluid-structure interaction: A case study for aortic aneurysm.Computers in biology and medicine · 2025Article
- DIRECT MEDICAL IMAGE TO SIMULATION USING AUTO-SEGMENTATION AND POINT CLOUD-BASED CFD.Advances in computational science and engineering · 2025Article
- Cardiac remodeling and antihypertensive medication changes after thoracic endovascular aortic repair vs open surgical repair.Journal of vascular surgery · 2025Article
- Three-dimensional characterization of ascending aortic strain, motion and growth in patients undergoing thoracic endovascular aortic repair.JVS-vascular science · 2025Article
- Computational Fluid-Structure Interaction in Microfluidics.Micromachines · 2024Review
- Patient-Specific Haemodynamic Analysis of Virtual Grafting Strategies in Type-B Aortic Dissection: Impact of Compliance Mismatch.Cardiovascular engineering and technology · 2024Article
- Endovascular Repair of Zone 0 Ascending Aortic Aneurysm: A Review of Current Knowledge and Developing Technology.Aorta (Stamford, Conn.) · 2024Article
- Ultrasound elastography to quantify average percent pressure-normalized strain reduction associated with different aortic endografts in 3D-printed hydrogel phantoms.JVS-vascular science · 2024Article
- Comparison of Two Generations of Thoracic Aortic Stent Grafts and Their Impact on Aortic Stiffness in anEJVES vascular forum · 2023Article
- Data-driven computational models of ventricular-arterial hemodynamics in pediatric pulmonary arterial hypertension.Frontiers in physiology · 2022Article
- AnFrontiers in cardiovascular medicine · 2022Article
- Left ventricular remodeling following aortic root and ascending aneurysm repair.Frontiers in cardiovascular medicine · 2022Article
- TEVAR and EVAR, the unknown knowns of the cardiovascular hemodynamics; and the immediate and long-term consequences of fabric material on major adverse clinical outcome.Frontiers in surgery · 2022Review
- The contemporary design of endovascular aneurysm stent-graft materials: PTFE versus polyester.Frontiers in surgery · 2022Review
Corrections and comments
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Authors and funding
9 authors at 5 institutions in 4 countries.
Funding
Abstract
objectivesCurrent endografts for thoracic endovascular aortic repair (TEVAR) are much stiffer than the aorta and have been shown to induce acute stiffening. In this study, we aimed to estimate the impact of TEVAR on left ventricular (LV) stroke work (SW) and mass using a non-invasive image-based workflow.
methodsThe University of Michigan database was searched for patients treated with TEVAR for descending aortic pathologies (2013-2016). Patients with available pre-TEVAR and post-TEVAR computed tomography angiography and echocardiography data were selected. LV SW was estimated via patient-specific fluid-structure interaction analyses. LV remodelling was quantified through morphological measurements using echocardiography and electrocardiographic-gated computed tomography angiography data.
resultsEight subjects were included in this study, the mean age of the patients was 68 (73, 25) years, and 6 patients were women. All patients were prescribed antihypertensive drugs following TEVAR. The fluid-structure interaction simulations computed a 26% increase in LV SW post-TEVAR [0.94 (0.89, 0.34) J to 1.18 (1.11, 0.65) J, P = 0.012]. Morphological measurements revealed an increase in the LV mass index post-TEVAR of +26% in echocardiography [72 (73, 17) g/m2 to 91 (87, 26) g/m2, P = 0.017] and +15% in computed tomography angiography [52 (46, 29) g/m2 to 60 (57, 22) g/m2, P = 0.043]. The post- to pre-TEVAR LV mass index ratio was positively correlated with the post- to pre-TEVAR ratios of SW and the mean blood pressure (ρ = 0.690, P = 0.058 and ρ = 0.786, P = 0.021, respectively).
conclusionsTEVAR was associated with increased LV SW and mass during follow-up. Medical device manufacturers should develop more compliant devices to reduce the stiffness mismatch with the aorta. Additionally, intensive antihypertensive management is needed to control blood pressure post-TEVAR.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.