ArticleGenome biology and evolution2019
Cycad Coralloid Roots Contain Bacterial Communities Including Cyanobacteria and Caulobacter spp. That Encode Niche-Specific Biosynthetic Gene Clusters.
Article in Genome biology and evolution, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed, 64 citations in OpenAlex.
- Conserved symbiosis-associated genes in the cycad Encephalartos natalensis suggest co-option for cyanobacterial symbiosis.The New phytologist · 2026Article
- Cyanobacterial biostimulants boost tomato (Solanum lycopersicum L.) Growth and drought tolerance for climate-resilient cropping systems.World journal of microbiology & biotechnology · 2026Article
- Nitrogen-fixing microbes gain genes in diverse types of living environments.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Distribution Pattern of EndangeredPlants (Basel, Switzerland) · 2025Article
- Chemical ecology of symbioses in cycads, an ancient plant lineage.The New phytologist · 2025Review
- Diversity and specificity of molecular functions in cyanobacterial symbionts.Scientific reports · 2024Article
- Phylometagenomics of cycad coralloid roots reveals shared symbiotic signals.Microbial genomics · 2024Article
- Gut microbiomes of cycad-feeding insects tolerant to β-methylamino-L-alanine (BMAA) are rich in siderophore biosynthesis.ISME communications · 2023Article
- Symbiosis between cyanobacteria and plants: from molecular studies to agronomic applications.Journal of experimental botany · 2023Review
- Core Endophytic Bacteria and Their Roles in the Coralloid Roots of CultivatedMicroorganisms · 2023Article
- Tolyporphins-Exotic Tetrapyrrole Pigments in a Cyanobacterium-A Review.Molecules (Basel, Switzerland) · 2023Review
- Plant-Environment Response Pathway Regulation Uncovered by Investigating Non-Typical Legume Symbiosis and Nodulation.Plants (Basel, Switzerland) · 2023Review
- Structure and Biosynthesis of Desmamides A-C, Lipoglycopeptides from the Endophytic CyanobacteriumJournal of natural products · 2022Review
- S2B, a Temperate Bacteriophage That Infects Caulobacter Crescentus Strain CB15.Current microbiology · 2022Article
- The genus Caulobacter and its role in plant microbiomes.World journal of microbiology & biotechnology · 2022Review
- Evolutionary genomic insights into cyanobacterial symbioses in plants.Quantitative plant biology · 2022Review
- Comparative Metagenomic Study of Rhizospheric and Bulk Mercury-Contaminated Soils in the Mining District of Almadén.Frontiers in microbiology · 2022Article
- Plant-growth-promoting Caulobacter strains isolated from distinct plant hosts share conserved genetic factors involved in beneficial plant-bacteria interactions.Archives of microbiology · 2021Article
- Identification of Putative Biosynthetic Gene Clusters for Tolyporphins in Multiple Filamentous Cyanobacteria.Life (Basel, Switzerland) · 2021Article
- Diversity, Phylogeny and Antagonistic Activity of Fungal Endophytes Associated with Endemic Species ofJournal of fungi (Basel, Switzerland) · 2021Article
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cycads are the only early seed plants that have evolved a specialized root to host endophytic bacteria that fix nitrogen. To provide evolutionary and functional insights into this million-year old symbiosis, we investigate endophytic bacterial sub-communities isolated from coralloid roots of species from Dioon (Zamiaceae) sampled from their natural habitats. We employed a sub-community co-culture experimental strategy to reveal both predominant and rare bacteria, which were characterized using phylogenomics and detailed metabolic annotation. Diazotrophic plant endophytes, including Bradyrhizobium, Burkholderia, Mesorhizobium, Rhizobium, and Nostoc species, dominated the epiphyte-free sub-communities. Draft genomes of six cyanobacteria species were obtained after shotgun metagenomics of selected sub-communities. These data were used for whole-genome inferences that suggest two Dioon-specific monophyletic groups, and a level of specialization characteristic of co-evolved symbiotic relationships. Furthermore, the genomes of these cyanobacteria were found to encode unique biosynthetic gene clusters, predicted to direct the synthesis of specialized metabolites, mainly involving peptides. After combining genome mining with detection of pigment emissions using multiphoton excitation fluorescence microscopy, we also show that Caulobacter species co-exist with cyanobacteria, and may interact with them by means of a novel indigoidine-like specialized metabolite. We provide an unprecedented view of the composition of the cycad coralloid root, including phylogenetic and functional patterns mediated by specialized metabolites that may be important for the evolution of ancient symbiotic adaptations.
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