Evidence map›Paper›PMID 30534677›Full record

ArticleLab on a chip2018

An inexpensive smartphone-based device for point-of-care ovulation testing.

Vaishnavi Potluri, Preethi Sangeetha Kathiresan, Hemanth Kandula, Prudhvi Thirumalaraju, Manoj Kumar Kanakasabapathy, Sandeep Kota Sai Pavan, Divyank Yarravarapu, Anand Soundararajan, Karthik Baskar, Raghav Gupta and 3 more

Registry-linked trialAbstract read
In one paragraph

Article in Lab on a chip, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07248046 (Comparing Cervical Mucus, PDG, LH, and Basal Body Temperature Combinations for Ovulation and Luteal Phase Identification Using the Premom Smartphone App Versus User-Read Test Results), which is not on this map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07248046 active not recruitingnot on this mapstarted 2026, after this paper: background citation

Comparing Cervical Mucus, PDG, LH, and Basal Body Temperature Combinations for Ovulation and Luteal Phase Identification Using the Premom Smartphone App Versus User-Read Test Results: A Prospective Observational Study

TypeobservationalSponsorBruyère Health Research Institute.Ran2026 to 2026Enrolled30ConditionsFertility, Mobile Applications, Artifical Intelligence, Cervical MucusArmsPremom App-Assisted Fertility Tracking
3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 49 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 2 countries.

Vaishnavi PotluriDivision of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA. hshafiee@bwh.harvard.edu.
Preethi Sangeetha Kathiresan
Hemanth Kandula
Prudhvi Thirumalaraju
Manoj Kumar Kanakasabapathy
Sandeep Kota Sai Pavan
Divyank Yarravarapu
Anand Soundararajan
Karthik Baskar
Raghav Gupta
Neeraj Gudipati
John C Petrozza
Hadi Shafiee
Brigham and Women's Hospital · USHarvard University · US

Funding

Translational Research Support CoreP30ES000002 · NIEHS · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI SUSAN A KORRICK · 1985 to 2026
$44.6M
Microchip for HBV testing using HIV-infected blood samplesR01AI138800 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI SHAFIEE, HADI · 2019 to 2023
$3.1M
Sensitive and quantitative point-of-care viral load testing on paperR01AI118502 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI SHAFIEE, HADI · 2016 to 2020
$2.2M
A home-based, rapid, sensitive semen analyzerR21HD092828 · NICHD · BRIGHAM AND WOMEN'S HOSPITAL · PI SHAFIEE, HADI · 2017 to 2018
$488k
NIAID NIH HHS R01 AI118502NIAID NIH HHS R01 AI138800NICHD NIH HHS R21 HD092828NIEHS NIH HHS P30 ES000002
6 · The paper itself

Abstract

The ability to accurately predict ovulation at-home using low-cost point-of-care diagnostics can be of significant help for couples who prefer natural family planning. Detecting ovulation-specific hormones in urine samples and monitoring basal body temperature are the current commonly home-based methods used for ovulation detection; however, these methods, relatively, are expensive for prolonged use and the results are difficult to comprehend. Here, we report a smartphone-based point-of-care device for automated ovulation testing using artificial intelligence (AI) by detecting fern patterns in a small volume (<100 μL) of saliva that is air-dried on a microfluidic device. We evaluated the performance of the device using artificial saliva and human saliva samples and observed that the device showed >99% accuracy in effectively predicting ovulation.

Indexed as

Point-of-Care TestingSmartphoneAdultArtificial IntelligenceEquipment DesignFemaleHumansModels, BiologicalOvulation DetectionSalivaYoung Adult

Identifiers

PMID30534677
PMCPMC6321627
OpenAlexW2904434892

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.