ArticleCommunications biology2018
Pre-obese children's dysbiotic gut microbiome and unhealthy diets may predict the development of obesity.
Article in Communications biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
57 citing papers in PubMed.
- Lifestyle modifications result in alterations in the gut microbiota in obese children.BMC microbiology · 2021Trial
- Microbial enterotypes beyond genus level:Gut microbes · 2020Trial
- Article
- The Gut Microbiota: An Essential Component in Understanding Pediatric Obesity: A Narrative Review.Nutrients · 2026Review
- Disrupted gut microbiome networks and unhealthy behaviors predict metabolic dysfunction in children and adolescents in the long term.iScience · 2026Article
- The abundance of gut bacterial families as an early marker of diet-induced metabolic shift: a study in young pre-obese rats and a hint to a potential prophylactic window.Frontiers in pharmacology · 2026Article
- Gut commensal Phascolarctobacterium faecium retunes innate immunity to mitigate obesity and metabolic disease in mice.Nature microbiology · 2025Article
- Offspring's exposome: a narrative review on the influence of early-life factors on childhood obesity risk.Frontiers in nutrition · 2025Review
- The role of probiotics in adolescents' obesity.Frontiers in cellular and infection microbiology · 2025Review
- Understanding the complex function of gut microbiota: its impact on the pathogenesis of obesity and beyond: a comprehensive review.Diabetology & metabolic syndrome · 2024Review
- Using the Behaviour Change Wheel and Theoretical Domains Framework to identify factors related to increasing fruit and vegetable consumption in children to guide future intervention development.Public health nutrition · 2024Article
- A 15-day pilot biodiversity intervention with horses in a farm system leads to gut microbiome rewilding in 10 urban Italian children.One health (Amsterdam, Netherlands) · 2024Article
- Review
- Review
- Article
- Establishment and perturbation of human gut microbiome: common trends and variations between Indian and global populations.Gut microbiome (Cambridge, England) · 2024Review
- Composition and evolution of the gut microbiota of growing puppies is impacted by their birth weight.Scientific reports · 2023Article
- Association of gut microbiota with obesity in children and adolescents.Clinical and experimental pediatrics · 2023Article
- Understanding the link between gut microbiota, dietary intake, and nutritional status in children with autism and typical development.Frontiers in nutrition · 2023Article
- Precision Nutrition: Recent Advances in Obesity.Physiology (Bethesda, Md.) · 2023Review
Corrections and comments
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Authors and funding
15 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
It is widely accepted that the intestinal microbiome is connected to obesity, as key mediator of the diet impact on the host metabolic and immunological status. To investigate whether the individual gut microbiome has a potential in predicting the onset and progression of diseases, here we characterized the faecal microbiota of 70 children in a two-time point prospective study, within a four-year window. All children had normal weight at the beginning of this study, but 36 of them gained excessive weight at the subsequent check-up. Microbiome data were analysed together with the hosts' diet information, physical activity, and inflammatory parameters. We find that the gut microbiota structures were stratified into a discrete number of groups, characterized by different biodiversity that correlates with inflammatory markers and dietary habits, regardless of age, gender, and body weight. Collectively, our data underscore the importance of the microbiome-host-diet configuration as a possible predictor of obesity.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.