Evidence map›Paper›PMID 30534435›Full record

ArticleArab journal of urology2018

Radical nephrectomy and intracaval thrombectomy for advanced renal cancer with extensive inferior vena cava involvement utilising cardiopulmonary bypass and hypothermic circulatory arrest: Is it worthwhile?

Hosam Serag, Jonathan M Featherstone, David F Griffiths, Dheeraj Mehta, John Dunne, Owen Hughes, Philip N Matthews

Open access · diamondAbstract read
In one paragraph

Article in Arab journal of urology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact, top 86% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Nephrectomy and IVC thrombectomy in renal cancer: a narrative review.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Hosam SeragDepartment of Urology, University Hospital of Wales, Heath Park, Cardiff, UK.
Jonathan M FeatherstoneDepartment of Urology, University Hospital of Wales, Heath Park, Cardiff, UK.
David F GriffithsDepartment of Pathology, University Hospital of Wales, Heath Park, Cardiff, UK.
Dheeraj MehtaDepartment of Cardiac Surgery, University Hospital of Wales, Heath Park, Cardiff, UK.
John DunneDepartment of Anaesthetics, University Hospital of Wales, Heath Park, Cardiff, UK.
Owen HughesDepartment of Urology, University Hospital of Wales, Heath Park, Cardiff, UK.
Philip N MatthewsDepartment of Urology, University Hospital of Wales, Heath Park, Cardiff, UK.
University Hospital of Wales · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo report our long-term outcomes of surgical treatment of renal tumours with inferior vena cava (IVC) tumour thrombus above the hepatic veins, utilising cardiopulmonary bypass (CBP) and hypothermic circulatory arrest (HCA), as surgical resection remains the only effective treatment for renal cancers with extensive IVC tumour thrombus. PATIENTS AND

methodsWe retrospectively reviewed 48 consecutive patients (median age 58 years) who underwent surgical treatment for non-metastatic renal cancer with IVC tumour thrombus extending above the hepatic veins. Perioperative, histological, disease-free (DFS) and overall survival (OS) data were recorded.

resultsTumour thrombus was level III in 23 patients and level IV in 25 patients. The median (range) CBP and HCA times were 162 (120-300) min and 35 (9-64) min, respectively. Three patients underwent synchronous cardiac surgical procedures. There were three (6.3%) perioperative deaths. American Society of Anesthesiologists grade and perioperative blood transfusion requirement were significant factors associated with perioperative death (

conclusionsRadical surgery for patients with extensive IVC tumour thrombus has acceptable operative morbidity and mortality. It provides symptom palliation and the possibility of long-term survival. Improvements in preoperative detection of occult metastasis may improve case selection and newer adjuvant therapies may improve survival in this high-risk group.

Indexed as

Advanced renal cancerASA, American Society of AnesthesiologistsCardiopulmonary bypassCPB, cardiopulmonary bypassDFS, disease-free survivalHCA, hypothermic circulatory arrestHypothermic circulatory arrestInferior vena cava thrombectomyIVC, inferior vena cavaLevel IV caval thrombusMOF, multi-organ failureOS, overall survival

Identifiers

PMID30534435
PMCPMC6277273
OpenAlexW2887120222

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.