Evidence map›Paper›PMID 30534398›Full record

ArticleNursing open2019

Beneficial effect of laughter therapy on physiological and psychological function in elders.

Yuki Yoshikawa, Etsuko Ohmaki, Hirohisa Kawahata, Yoshihiro Maekawa, Toshio Ogihara, Ryuichi Morishita, Motokuni Aoki

Registry-linked trialAbstract read
In one paragraph

Article in Nursing open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05601024 (The Effect of Laughter Therapy on Self-Esteem and Quality of Life in Patients With Stoma), which is not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05601024 nacompletednot on this mapstarted 2021, after this paper: background citation

The Effect of Laughter Therapy on Self-Esteem and Quality of Life in Patients With Stoma:Randomized Controlled Trial

TypeinterventionalSponsorIstanbul University - CerrahpasaRan2021 to 2023Enrolled66ConditionsStoma Colostomy, Stoma IleostomyArmsLaughter Therapy
3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Beyond tumor biology: nursing interventions for psychological and immune health in cancer patients.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Review
  2. Review
  3. Article
  4. Teaching comprehension of double-meaning jokes to young children.Journal of applied behavior analysis · 2021
    Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yuki YoshikawaGraduate School of Health Sciences Morinomiya University of Medical Sciences Suminoe-ku Japan.
Etsuko OhmakiGraduate School of Health Sciences Morinomiya University of Medical Sciences Suminoe-ku Japan.
Hirohisa KawahataGraduate School of Health Sciences Morinomiya University of Medical Sciences Suminoe-ku Japan.
Yoshihiro MaekawaGraduate School of Health Sciences Morinomiya University of Medical Sciences Suminoe-ku Japan.
Toshio OgiharaGraduate School of Health Sciences Morinomiya University of Medical Sciences Suminoe-ku Japan.
Ryuichi MorishitaDepartment of Clinical Gene Therapy, Graduate School of Medicine Osaka University Suita Japan.
Motokuni AokiGraduate School of Health Sciences Morinomiya University of Medical Sciences Suminoe-ku Japan.ORCID 0000-0002-3912-3222

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimIn the present study we investigated the effect of laughter therapy on physiological and psychological function in older people.

designAn open-label trial.

methodsSeventeen older people who regularly attended an elderly day care centre were recruited. Stand-up comedy as laughter therapy was performed once a week for 4 weeks. Parameters of physiological and psychological function were evaluated before and after laughter therapy.

resultsLaughter therapy intervention resulted in a significant reduction in systolic blood pressure and heart rate, accompanied by a significant increase in plasma concentration of serotonin and a significant decrease in salivary concentration of chromogranin A. Questionnaire surveys of SF-8, GDS-15, and Vitality Index demonstrated alleviation of depression and improvement of sociability and activity in older people. Laughter therapy could be expected to become a practical treatment to improve quality of life of older people in an elderly day care centre.

Indexed as

blood pressuregeriatric depression scale (GDS)laughter therapyquality of life (QOL)serotoninSF‐8

Identifiers

PMID30534398
PMCPMC6279721

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.