Evidence map›Paper›PMID 30534379›Full record

ArticlePharmacology research & perspectives2018

Pharmacological profile of the neuropeptide S receptor: Dynamic mass redistribution studies.

Chiara Ruzza, Federica Ferrari, Remo Guerrini, Erika Marzola, Delia Preti, Rainer K Reinscheid, Girolamo Calo

Open access · goldAbstract readEvaluation Study
In one paragraph

Article in Pharmacology research & perspectives, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.4field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Frontiers in pharmacology · 2023
    Article
  3. Review
  4. Article
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Chiara RuzzaDepartment of Medical Sciences Section of Pharmacology National Institute of Neuroscience University of Ferrara Ferrara Italy.
Federica FerrariDepartment of Medical Sciences Section of Pharmacology National Institute of Neuroscience University of Ferrara Ferrara Italy.
Remo GuerriniDepartment of Chemical and Pharmaceutical Sciences and LTTA University of Ferrara Ferrara Italy.
Erika MarzolaDepartment of Chemical and Pharmaceutical Sciences and LTTA University of Ferrara Ferrara Italy.
Delia PretiDepartment of Chemical and Pharmaceutical Sciences and LTTA University of Ferrara Ferrara Italy.
Rainer K ReinscheidInstitute of Pharmacology and Toxicology Jena University Hospital Friedrich Schiller University Jena Jena Germany.
Girolamo CaloDepartment of Medical Sciences Section of Pharmacology National Institute of Neuroscience University of Ferrara Ferrara Italy.
University of Ferrara · ITUniversity of Münster · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neuropeptide S (NPS) is the endogenous ligand of the neuropeptide S receptor (NPSR). NPS modulates several biological functions including anxiety, wakefulness, pain, and drug abuse. The aim of this study was the investigation of the pharmacological profile of NPSR using the dynamic mass redistribution (DMR) assay. DMR is a label-free assay that offers a holistic view of cellular responses after receptor activation. HEK293 cells stably transfected with the murine NPSR (HEK293

Indexed as

Biological AssayBiosensing TechniquesCalciumDepsipeptidesDrug Evaluation, PreclinicalHEK293 CellsHumansLigandsPertussis ToxinReceptors, NeuropeptideRolipramSignal TransductionCalciumDepsipeptidesFR900359Ligandsneuropeptide S receptor, mousePertussis ToxinReceptors, NeuropeptideRolipramdynamic mass redistribution assayin vitro pharmacologylabel‐free assayneuropeptide Sneuropeptide S receptor

Identifiers

PMID30534379
PMCPMC6277375
OpenAlexW2903246640

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.