Evidence map›Paper›PMID 30534369›Full record

ArticleLight, science & applications2018

Neuronal photoactivation through second-harmonic near-infrared absorption by gold nanoparticles.

Wieteke D A M de Boer, Jan J Hirtz, Antonio Capretti, Tom Gregorkiewicz, Mercè Izquierdo-Serra, Shuting Han, Christophe Dupre, Yuriy Shymkiv, Rafael Yuste

Abstract read
In one paragraph

Article in Light, science & applications, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Time for NanoNeuro.Nature methods · 2021
    Review
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Wieteke D A M de Boer *1NeuroTechnology Center, Department of Biological Sciences, Columbia University, New York, NY 10027 USA.
Jan J Hirtz *1NeuroTechnology Center, Department of Biological Sciences, Columbia University, New York, NY 10027 USA.
Antonio Capretti2Van der Waals-Zeeman Institute, University of Amsterdam, 1098 XH Amsterdam, Netherlands.ORCID 0000-0002-6705-9280
Tom Gregorkiewicz2Van der Waals-Zeeman Institute, University of Amsterdam, 1098 XH Amsterdam, Netherlands.
Mercè Izquierdo-Serra1NeuroTechnology Center, Department of Biological Sciences, Columbia University, New York, NY 10027 USA.
Shuting Han1NeuroTechnology Center, Department of Biological Sciences, Columbia University, New York, NY 10027 USA.
Christophe Dupre1NeuroTechnology Center, Department of Biological Sciences, Columbia University, New York, NY 10027 USA.ORCID 0000-0002-5929-8492
Yuriy Shymkiv1NeuroTechnology Center, Department of Biological Sciences, Columbia University, New York, NY 10027 USA.
Rafael Yuste1NeuroTechnology Center, Department of Biological Sciences, Columbia University, New York, NY 10027 USA.

Funding

IMAGING FUNCTIONAL CONNECTIVITY IN VISUAL CORTEXR01EY011787 · NEI · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI YUSTE, RAFAEL · 1998 to 2021
$6.4M
CELLULAR AND MOLECULAR FOUNDATIONS OF BIOMEDICAL SCIENCET32GM008798 · NIGMS · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI PRYWES, RON M · 2001 to 2018
$6.3M
Functional connectomics of the neocortical microcircuitDP1EY024503 · NEI · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI YUSTE, RAFAEL · 2013 to 2017
$4.0M
Effect of GABAergic inhibition of dendritic spines on synaptic pruning in the medial prefrontal cortex during adolescenceR01MH115900 · NIMH · SUNY DOWNSTATE MEDICAL CENTER · PI SMITH, SHERYL S · 2019 to 2023
$3.2M
Two-photon optical control of astrocytic functionR01MH101218 · NIMH · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI YUSTE, RAFAEL · 2013 to 2017
$2.0M
CRCNS: Modeling the nanophysiology of dendritic spinesR01NS110422 · NINDS · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI YUSTE, RAFAEL · 2018 to 2020
$744k
NEI NIH HHS DP1 EY024503NEI NIH HHS R01 EY011787NIGMS NIH HHS T32 GM008798NIMH NIH HHS R01 MH101218NIMH NIH HHS R01 MH115900NINDS NIH HHS R01 NS110422
6 · The paper itself

Abstract

Optical activation of neurons requires genetic manipulation or the use of chemical photoactivators with undesirable side effects. As a solution to these disadvantages, here, we demonstrate optically evoked neuronal activity in mouse cortical neurons in acute slices and in vivo by nonlinear excitation of gold nanoparticles. In addition, we use this approach to stimulate individual epitheliomuscular cells and evoke body contractions in

Identifiers

PMID30534369
PMCPMC6279767

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.