ArticlePerioperative medicine (London, England)2018
Characterizing post-extubation negative pressure pulmonary edema in the operating room-a retrospective matched case-control study.
Article in Perioperative medicine (London, England), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 18 citations in OpenAlex.
- Review
- Postextubation negative-pressure pulmonary edema after an appendectomy.Radiology case reports · 2025Article
- Extubation and removal of supraglottic airway devices in pediatric anesthesia.Anesthesia and pain medicine · 2024Article
- Negative pressure pulmonary edema: a case report and literature review.Frontiers in medicine · 2024Article
- Article
- Prediction of Postoperative Pulmonary Edema Risk Using Machine Learning.Journal of clinical medicine · 2023Article
- Point of Care Ultrasound-Diagnostic Approach of an Atypical Negative Pressure Pulmonary Oedema.Turkish journal of anaesthesiology and reanimation · 2022Article
- Near-fatal negative pressure pulmonary oedema successfully treated with venovenous extracorporeal membrane oxygenation performed in the hybrid emergency room.BMJ case reports · 2020Article
- Negative pressure pulmonary edema after general anesthesia using the i-gel.Saudi journal of anaesthesiaArticle
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPost-extubation negative pressure pulmonary edema (NPPE) is an uncommon but important anesthesia-related emergency presenting with acute respiratory distress and hypoxemia after removal of airway devices. This study investigated the incidence and associated risk factors for post-extubation NPPE during emergence.
methodsThis retrospective, matched case-control study was conducted by reviewing the post-anesthesia records in Tzu Chi General Hospital, Taiwan. Patients reported of having acute hypoxemia (SpO
resultsA total of 85,561 patients received general anesthesia with airway instrumentation during the 8.5-year study period. A total of 16 patients were identified as definite cases of NPPE. Compared with the matched controls (
conclusionWe present the first clinical comparative study demonstrating that the overall incidence of NPPE immediately after extubation in the operating room is 0.019%. Our results highlight that active smokers and patients receiving endotracheal intubation general anesthesia are associated with significantly higher risks of developing NPPE following extubation in the operating room.
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