Evidence map›Paper›PMID 30534284›Full record

ArticleJournal of cardiology cases2013

Sick sinus syndrome induced by interferon and ribavirin therapy in a patient with chronic hepatitis C.

Masao Sakabe, Ryozo Yoshioka, Akira Fujiki

Open access · bronzeAbstract read
In one paragraph

Article in Journal of cardiology cases, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 45 citations in OpenAlex.

  1. Pooled it
  2. Current research in microbial sciences · 2026
    Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Cardiovascular impact of COVID-19: an array of presentations.Acta bio-medica : Atenei Parmensis · 2021
    Article
  8. Review
  9. Review
  10. Review
  11. Review
  12. Review
  13. Review
  14. Association between COVID-19 and cardiovascular disease.International journal of cardiology. Heart & vasculature · 2020
    Review
  15. Coronavirus disease 2019 and cardiovascular system: A narrative review.International journal of cardiology. Heart & vasculature · 2020
    Review
  16. Review
  17. Review
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Masao SakabeDivision of Cardiology, Shizuoka Red Cross Hospital, 8-2 Otemachi, Aoi-ku, Shizuoka 420-0853, Japan.
Ryozo YoshiokaDivision of Cardiology, Shizuoka Red Cross Hospital, 8-2 Otemachi, Aoi-ku, Shizuoka 420-0853, Japan.
Akira FujikiDivision of Cardiology, Shizuoka Red Cross Hospital, 8-2 Otemachi, Aoi-ku, Shizuoka 420-0853, Japan.
Shizuoka Red Cross Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The therapeutic effect of interferon (IFN) on chronic hepatitis C and its adverse effects have been well documented. Although the incidence of IFN-related cardiotoxicity is low, careful observation is necessary because of its possible fatal outcome. We describe a 45-year-old woman who suffered from sinus node dysfunction after the combination therapy of pegylated IFN-alpha and ribavirin for chronic hepatitis C. Despite the cessation of IFN therapy, sinus node dysfunction was not reversible, and led her to the implantation of permanent pacemaker. Physicians should therefore be aware of the possibility of sinus node dysfunction in patients receiving IFN therapy. <

Indexed as

Chronic hepatitis CInterferonSick sinus syndromeSide effect

Identifiers

PMID30534284
PMCPMC6277810
OpenAlexW2045983943

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.