Evidence map›Paper›PMID 30534201›Full record

ArticleBiotechnology for biofuels2018

Metabolic engineering of the thermophilic filamentous fungus

Shuying Gu, Jingen Li, Bingchen Chen, Tao Sun, Qian Liu, Dongguang Xiao, Chaoguang Tian

Open access · goldAbstract read
In one paragraph

Article in Biotechnology for biofuels, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 78 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Heterologous protein production in filamentous fungi.Applied microbiology and biotechnology · 2023
    Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Microorganisms · 2022
    Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Transcriptional Profiling ofFrontiers in microbiology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Shuying Gu *1College of Biotechnology, Tianjin University of Science and Technology, Tianjin, 300457 China.
Jingen Li *2Key Laboratory of Systems Microbial Biotechnology, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, 300308 China.
Bingchen Chen2Key Laboratory of Systems Microbial Biotechnology, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, 300308 China.
Tao Sun2Key Laboratory of Systems Microbial Biotechnology, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, 300308 China.
Qian Liu2Key Laboratory of Systems Microbial Biotechnology, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, 300308 China.
Dongguang Xiao1College of Biotechnology, Tianjin University of Science and Technology, Tianjin, 300457 China.
Chaoguang Tian2Key Laboratory of Systems Microbial Biotechnology, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, 300308 China.
Chinese Academy of Sciences · CNTianjin University of Science and Technology · CNTianjin Institute of Industrial Biotechnology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFumaric acid is widely used in food and pharmaceutical industries and is recognized as a versatile industrial chemical feedstock. Increasing concerns about energy and environmental problems have resulted in a focus on fumaric acid production by microbial fermentation via bioconversion of renewable feedstocks. Filamentous fungi are the predominant microorganisms used to produce organic acids, including fumaric acid, and most studies to date have focused on

resultsWe explored the feasibility of producing fumarate by metabolically engineering

conclusionsThis is the first metabolic engineering study on the production of fumaric acid by the thermophilic filamentous fungus

Indexed as

CRISPR/Cas9Fumaric acidMetabolic engineeringMyceliophthora thermophilaReductive TCA

Identifiers

PMID30534201
PMCPMC6278111
OpenAlexW2903545169

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.