ArticleJournal of geriatric cardiology : JGC2018
Increased index of microcirculatory resistance in older patients with heart failure with preserved ejection fraction.
Article in Journal of geriatric cardiology : JGC, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
9 citing papers in PubMed.
- Autoregulation of the Coronary Microcirculation in the Presence or Absence of Large Pericardial Effusion.JACC. Case reports · 2025Article
- Partial Regulation of Ketone Metabolism by Hypoxia in H9C2 Cardiomyocytes.Current medical science · 2025Article
- Exploring coronary microvascular dysfunction from functional impairment and structural damage.Frontiers in cardiovascular medicine · 2025Review
- The prognostic role of galectin-3 and endothelial function in patients with heart failure.Cardiology journal · 2023Article
- The Role of Systemic Microvascular Dysfunction in Heart Failure with Preserved Ejection Fraction.Biomolecules · 2022Review
- Unveiling the role of exercise training in targeting the inflammatory paradigm of heart failure with preserved ejection fraction: a narrative review.Heart failure reviews · 2022Review
- Advances in Journal of Geriatric Cardiology over the course of a decade.Journal of geriatric cardiology : JGC · 2020Article
- Exploring Associations Between Cardiac Structure and Retinal Vascular Geometry.Journal of the American Heart Association · 2020Article
- Microvascular Dysfunction in Heart Failure With Preserved Ejection Fraction.Frontiers in physiology · 2019Review
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo study the coronary microvascular function in older patients with heart failure with preserved ejection fraction (HFpEF) using an invasive pressure-temperature sensor guidewire.
methodsPatients undergoing echocardiography and cardiac catheterization examinations for exertional dyspnea and a positive stress test were retrospectively enrolled from January 2014 to November 2017, and were allocated into the control group or HFpEF group. The HFpEF group was secondary divided into two groups according to the age of 65. Comparing the clinical features and values obtained in examinations between the three groups, multivariate regression analysis was used to analyze the predictors of left ventricle end diastolic pressure (LVEDP).
resultsThere were 87 patients enrolled in this study. The older HFpEF patients (
conclusionsAn increased IMR and reduced CFR were characteristics of microvascular dysfunction in older HFpEF patients. The IMR independently had a positive linear correlation with LVEDP. Microvascular rarefaction might be a subsequent pathological progression in the development of HFpEF.
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Registered trials
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