ArticleFrontiers in neurology2018
Stereotactic Lesioning of the Thalamic Vo Nucleus for the Treatment of Writer's Cramp (Focal Hand Dystonia).
Article in Frontiers in neurology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 20 citations in OpenAlex.
- Focused Ultrasound Ablation for Neurological Disorders.Biological psychiatry · 2026Review
- Magnetic resonance-guided focused ultrasound in dystonia: a scoping review.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025Article
- The thalamus: Structure, function, and neurotherapeutics.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2025Review
- Primary Cueing Tremor: A Task-Specific Tremor of Billiard Players.Tremor and other hyperkinetic movements (New York, N.Y.) · 2025Article
- Thalamic ventral-Oralis complex/rostral zona incerta deep brain stimulation for midline tremor.Journal of neurology · 2024Article
- Review
- Pistol Shooting Dystonia Treated with Thalamotomy.Tremor and other hyperkinetic movements (New York, N.Y.) · 2023Article
- Novel targets in deep brain stimulation for movement disorders.Neurosurgical review · 2022Review
- Dystonia and Cerebellum: From Bench to Bedside.Life (Basel, Switzerland) · 2021Review
- Case Report: Deep Cerebellar Stimulation for Tremor and Dystonia.Frontiers in neurology · 2021Article
- Deep Brain Stimulation of the Ventral Intermediate Nucleus of the Thalamus in Writer's Cramp: A Case Report.Tremor and other hyperkinetic movements (New York, N.Y.) · 2021Article
- Treatment of Dystonia: Medications, Neurotoxins, Neuromodulation, and Rehabilitation.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2020Review
- Treatment of dystonia and tics.Clinical parkinsonism & related disorders · 2020Review
- The neurobiological basis for novel experimental therapeutics in dystonia.Neurobiology of disease · 2019Review
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Writer's cramp (focal hand dystonia) is a sporadic focal dystonia that affects a specific part of the upper limb causing excessive co-contraction of antagonistic muscles. It usually presents as a task-specific dystonia, including, among others, writing of a character or playing a musical instrument. Although treatments for writer's cramp exist, medical therapy often results in unsatisfactory outcomes in patients with this type of dystonia. However, accumulating evidence suggests that long-term and complete remission of various types of focal hand dystonia can be achieved with stereotactic ablation or deep brain stimulation of the thalamic ventral-oralis complex (Vo) nucleus, which includes both the ventralis oralis posterior and anterior nuclei of the thalamus. Following the striking therapeutic success of Vo thalamotomy in patients with medically-refractory writer's cramp, we here introduce the use of stereotactic lesioning of the thalamic Vo nucleus for the treatment of this focal type of dystonia. Our findings identified patients with disabling writer's cramp (i.e., it prevents their success in their professional careers) to be good candidates for positive outcome with this surgical technique.
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