Evidence map›Paper›PMID 30534040›Full record

ArticleInternational journal of health sciences

New strains of hepatitis B virus genotype E circulating in Nigeria.

Bankole H Oladeinde, Ifeoma M Ekejindu, Richard Omoregie, Ikpomwonosa Odia, Obiora D Aguh, Uchechukwu M Okwu

Open access · greenAbstract read
PubMed Full text at PMC
In one paragraph

Article in International journal of health sciences. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 1 country.

Bankole H OladeindeDepartment of Medical Laboratory Science, Edo University, Iyamho, Edo State, Nigeria.
Ifeoma M EkejinduDepartment of Medical Laboratory Sciences, Faculty of Health Sciences, College of Health Science, Nnamdi Azikiwe University, Awka, Nigeria.
Richard OmoregieSchool of Medical Laboratory Sciences, University of Benin Teaching Hospital, Benin City, Nigeria.
Ikpomwonosa OdiaInstitute of Lassa Fever Research and Control, Irrua Specialist Hospital, Irrua, Edo State, Nigeria.
Obiora D AguhMedical Microbiology Unit, Medical Laboratory Services, University of Benin Teaching Hospital, Benin City, Nigeria.
Uchechukwu M OkwuDepartment of Biological Sciences (Microbiology), College of Natural and Applied Sciences, Igbinedion University, Okada, Edo State, Nigeria.
University of Benin Teaching Hospital · NGEdo State University Uzairue · NGIgbinedion University · NGIrrua Specialist Teaching Hospital · NGNnamdi Azikiwe University · NG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveHepatitis B virus (HBV) is not uncommon among persons infected with human immunodeficiency virus (HIV). Severity of HBV infection and treatment outcome are associated with specific HBV genotypes. No study has reported the types of HBV genotypes circulating among HIV-infected subjects in Nigeria. This study was designed to determine the prevalence of HBV, as well as its genotypic distribution among HIV-infected subjects in Benin City, Nigeria.

methodsWhole blood was collected from a total of 564 HIV-infected and 250 apparently healthy HIV-negative subjects. Serodiagnosis of HBV infection was done using an immunochromatographic kit. Detection of HBV-DNA and sequencing of amplicons were done using standard molecular techniques.

resultsHIV status was not significantly associated with HBV seroinfection (HIV vs. non-HIV: 4.6% vs. 4.0%; odds ratio = 1.168, 95% confidence interval = 0.550, 2.444, and P = 0.854). HIV-infected subjects were observed to have an insignificantly (P = 0.645) higher prevalence of true HBV infection than their non-HIV-infected counterparts (HIV positive vs. HIV negative: 23.1% vs. 10.0%). All patients with true HBV infection were found to harbor HBV genotype E, which did not cluster around other HBV genotype E.

conclusionThis study reports novel strains of HBV genotype E circulating in Nigeria.

Indexed as

Hepatitis B virus genotypeshuman immunodeficiency virus infected patientsNigeria

Identifiers

PMID30534040
PMCPMC6257873
OpenAlexW2898618627

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.