Evidence map›Paper›PMID 30534013›Full record

ArticleReports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology

Lymph flow guided irradiation of regional lymph nodes in patients with cervical cancer: Preliminary analysis of scintigraphic data.

Sergey Nikolaevich Novikov, Pavel Ivanovich Krzhivitskii, Sergey Vasilevich Kanaev, Igor Viktorovitch Berlev, Margarita Viktorovna Kargopolova, Zaur Ibragimov, Mikhail Bisyarin, Valentina Vladimirovna Saveleva

Open access · diamondAbstract read
In one paragraph

Article in Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. New developments and controversies in cervical cancer.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Sergey Nikolaevich NovikovDepartment of Radiation Oncology & Nuclear Medicine, N.N. Petrov Institute Oncology, Leningradskaya 68, 197758 St Petersburg, Russia.
Pavel Ivanovich KrzhivitskiiDepartment of Radiation Oncology & Nuclear Medicine, N.N. Petrov Institute Oncology, Leningradskaya 68, 197758 St Petersburg, Russia.
Sergey Vasilevich KanaevGroups of Radiology, Radiation Oncology & Nuclear Medicine, N.N. Petrov Institute Oncology, Leningradskaya 68, 197758 St Petersburg, Russia.
Igor Viktorovitch BerlevDepartment of Oncogynecology, N.N. Petrov Institute Oncology, Leningradskaya 68, 197758 St Petersburg, Russia.
Margarita Viktorovna KargopolovaDepartment of Radiation Oncology & Nuclear Medicine, N.N. Petrov Institute Oncology, Leningradskaya 68, 197758 St Petersburg, Russia.
Zaur IbragimovDepartment of Oncogynecology, N.N. Petrov Institute Oncology, Leningradskaya 68, 197758 St Petersburg, Russia.
Mikhail BisyarinDepartment of Radiation Oncology & Nuclear Medicine, N.N. Petrov Institute Oncology, Leningradskaya 68, 197758 St Petersburg, Russia.
Valentina Vladimirovna SavelevaDepartment of Radiation Oncology & Nuclear Medicine, N.N. Petrov Institute Oncology, Leningradskaya 68, 197758 St Petersburg, Russia.
Institute of Oncology NN Petrov · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate patterns of lymph flow from primary lesions in patients with cervical cancer and to determine how useful for radiotherapy planning this information can be. MATERIALS AND

methodsSPECT-CT visualization of sentinel (SLN) lymph nodes (LNs) was performed in 36 primary patients with IB-IIB cervical cancer. The acquisition started 120-240 min after 4 peritumoral injections of 99mTc-radiocolloids (150-300 MBq in 0.4-1 ml). We determined localization of LN with uptake of radiocolloids, type of lymph flow (mono-, bi-lateral) and lymph flow patterns (supraureteral paracervical, infraureteral paracervical and directly to para-aortic LNs).

resultsSLNs were visualized in 31 of 36 women. Bilateral lymph-flow was detected in 22 (71%), monolateral - in the other 9 (29%) cases. The distribution of SLNs was as follows: external iliac - 64.5%, internal iliac - 54.8%, obturator - 32.2%, common iliac - 35.5% and pre-sacral 3.2%. Para-aortic LNs were visualized in 5 (16.1%) patients. The supraureteral paracervical pattern of lymph flow was identified in 22, infraureteral paracervical - in 4 and their combination - in the other 5 women.

conclusionVisualization of an individual pattern of lymph flow from primary cervical cancer can be considered as a promising tool for optimization of the volume of irradiated regional LNs.

Indexed as

Cervical cancerLymph flowRadiotherapySentinel lymph nodesSPECT–CT

Identifiers

PMID30534013
PMCPMC6277276
OpenAlexW2808296707

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.