ArticleJAMA network open2018
Effect of Internet-based Cognitive Behavioral Humanistic and Interpersonal Training vs. Internet-based General Health Education on Adolescent Depression in Primary Care: A Randomized Clinical Trial.
Article in JAMA network open, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.
- Heterogeneity of Treatment Effects in Internet- and Mobile-Based Interventions for Depression: A Systematic Review and Meta-Analysis.JAMA network open · 2024Pooled it
- A whole-of-society approach to depression prevention during the global pandemic: Preliminary data from three large-scale trials.Journal of consulting and clinical psychology · 2025Trial
- Online positive parenting programme for promoting parenting competencies and skills: randomised controlled trial.Scientific reports · 2024Trial
- Online positive parenting programme for promoting parenting competencies and skills: randomised controlled trial.Scientific reports · 2022Trial
- 24-Month Outcomes of Primary Care Web-Based Depression Prevention Intervention in Adolescents: Randomized Clinical Trial.Journal of medical Internet research · 2020Trial
- Randomized Clinical Trial of an Internet-Based Adolescent Depression Prevention Intervention in Primary Care: Internalizing Symptom Outcomes.International journal of environmental research and public health · 2020Trial
- Examining the Effectiveness of a Web-Based Intervention for Depressive Symptoms in Female Adolescents: Applying Social Cognitive Theory.Journal of research in health sciences · 2019Trial
- Clinicians' provision of a self-guided digital mental health intervention to adolescents with depressive symptoms at preventive health visits in California.Preventive medicine reports · 2026Article
- Validating a digital depression prevention program for adolescents in Jordan: cultural adaptation and user testing in a randomized controlled trial.Frontiers in psychiatry · 2025Article
- PATHway: Intervention optimization of a prevention program for adolescents at-risk for depression in the primary care setting.Contemporary clinical trials · 2024Article
- Article
- Servant leadership, brand love, and work ethic: important predictors of general health in workers in the education sector.Frontiers in psychology · 2024Article
- Efficacy of internet-based cognitive-behavioral therapy for depression in adolescents: A systematic review and meta-analysis.Internet interventions · 2023Review
- Digital technologies to support adolescents with depression and anxiety: review.BJPsych advances · 2023Review
- Appropriate Use and Operationalization of Adherence to Digital Cognitive Behavioral Therapy for Depression and Anxiety in Youth: Systematic Review.JMIR mental health · 2022Review
- Dyadic Psychosocial eHealth Interventions: Systematic Scoping Review.Journal of medical Internet research · 2020Article
- Primary care-based screening and recruitment for an adolescent depression prevention trial: Contextual considerations during a youth mental health crisis.Implementation research and practiceArticle
- Effectiveness of internet-delivered psychological treatments for children and adolescents with anxiety and/or depressive disorders: Systematic review and network meta-analysis.International journal of clinical and health psychology : IJCHPArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
24 authors at 15 institutions in 5 countries.
Funding
Abstract
importanceAlthough 13-20% of American adolescents experience a depressive episode annually, no scalable primary care model for adolescent depression prevention is currently available.
objectiveTo study whether CATCH-IT (Competent Adulthood Transition with Cognitive Behavioral Humanistic and Interpersonal Training) reduces the hazard for depression in at-risk adolescents identified in primary care, as compared to a general health education attention control (HE).
designThe Promoting AdolescenT Health (PATH) study compares CATCH-IT and HE in a phase 3 single-blind multicenter randomized attention control trial. Participants were enrolled from 2012 to 2016 and assessed at 2, 6, 12, 18, and 24 months post-randomization.
settingPrimary care.
participantsEligible adolescents were 13-18 years with subsyndromal depression and/or history of depression and no current depression diagnosis or treatment. Of 2,250 adolescents screened for eligibility, 446 participants completed the baseline interview and 369 were randomized into CATCH-IT (n=193) and HE (n=176).
interventionsCATCH-IT is a 20-module (15 adolescent modules, 5 parent modules) online psychoeducation course that includes a parent program, supported by three motivational interviews. MAIN OUTCOMES AND MEASURES: Time-to-event for depressive episode; depressive symptoms at 6 months.
resultsMean age was 15.4 years, and 68% were female; 28% had both a past episode and subsyndromal depression; 12% had a past episode only, 59% had subsyndromal depression only, and 1% had borderline subsyndromal depression. The outcome of time-to-event favored CATCH-IT but was not significant with intention-to-treat analyses (N=369; CONCLUSIONS AND RELEVANCE: CATCH-IT may be better than HE for preventing depressive episodes for at-risk adolescents with sub-syndromal depression. CATCH-IT may be a scalable approach to prevent depressive episodes in adolescents in primary care.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.