ArticleJournal of the Belgian Society of Radiology2018
Relationship between Injection Rate and Contrast Enhancement on Three-dimensional Digital Subtraction Angiography of the Cerebral Arteries.
Article in Journal of the Belgian Society of Radiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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2 citing papers in PubMed, 6 citations in OpenAlex.
- Efficiency and Optimization of Iodinated Contrast Agents in Cerebral Aneurysm CT Angiography: A Systematic Review.Diagnostics (Basel, Switzerland) · 2026Review
- Effects of contrast medium injection pressure on angiographic image quality.Frontiers in radiology · 2025Article
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2 authors at 2 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
objectiveThree-dimensional (3D) digital subtraction angiography (DSA) is becoming a common technique for the assessment of the cerebral arteries. Nevertheless, the injection parameters for each artery are not standardized among institutions. The objective of this study was to analyze the relationship between injection rate and contrast enhancement on 3D DSA of the common carotid artery. MATERIALS AND
methodsTwenty-four patients who underwent 3D DSA of the common carotid artery from June 2013 to March 2015 were included in this retrospective study. Contrast enhancement of each patient was analyzed for four cerebral arteries segments (A1, A2, M1 and M2) by measuring the average pixel value on the source rotational two-dimensional DSA images. Linear regression analysis was used to investigate the correlation between injection rate and contrast enhancement.
resultsAll four regression lines showed that a higher injection rate led to higher contrast enhancement. There was a significant relationship for the A1, A2 and M1 segments (P = 0.008, 0.03 and < 0.001) but not for the M2 segment (P = 0.13). The goodness-of-fit of the regression lines was high for the M1 segment (R
conclusionIn 3D DSA of the common carotid artery, contrast enhancement of a relatively wide lumen could be optimized by adjusting the injection rate. However, it is difficult to optimize the contrast enhancement of a relatively narrow lumen only by adjusting the injection rate.
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