Evidence map›Paper›PMID 30533598›Full record

ArticleJournal of healthcare informatics research2018

Nearest Consensus Clustering Classification to Identify Subclasses and Predict Disease.

Awad A Alyousef, Svetlana Nihtyanova, Chris Denton, Pietro Bosoni, Riccardo Bellazzi, Allan Tucker

Abstract read
In one paragraph

Article in Journal of healthcare informatics research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

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  13. Use of Machine Learning Consensus Clustering to Identify Distinct Subtypes of Kidney Transplant Recipients With DGF and Associated Outcomes.Transplant international : official journal of the European Society for Organ Transplantation · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Awad A Alyousef1Department Computer Science, Brunel University London, Uxbridge, UK.
Svetlana Nihtyanova2UCL Royal Free Hospital, London, UK.
Chris Denton2UCL Royal Free Hospital, London, UK.
Pietro Bosoni3University of Pavia, Pavia, Italy.
Riccardo Bellazzi3University of Pavia, Pavia, Italy.
Allan Tucker1Department Computer Science, Brunel University London, Uxbridge, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Disease subtyping, which helps to develop personalized treatments, remains a challenge in data analysis because of the many different ways to group patients based upon their data. However, if we can identify subclasses of disease, then it will help to develop better models that are more specific to individuals and should therefore improve prediction and understanding of the underlying characteristics of the disease in question. This paper proposes a new algorithm that integrates consensus clustering methods with classification in order to overcome issues with sample bias. The new algorithm combines K-means with consensus clustering in order build cohort-specific decision trees that improve classification as well as aid the understanding of the underlying differences of the discovered groups. The methods are tested on a real-world freely available breast cancer dataset and data from a London hospital on systemic sclerosis, a rare potentially fatal condition. Results show that "nearest consensus clustering classification" improves the accuracy and the prediction significantly when this algorithm has been compared with competitive similar methods.

Indexed as

ClassificationConsensus clusteringDisease subgroup discovery

Identifiers

PMID30533598
PMCPMC6245235

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.