ReviewBioactive materials2019
A comprehensive review of biodegradable synthetic polymer-ceramic composites and their manufacture for biomedical applications.
Review in Bioactive materials, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 103 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
103 citing papers in PubMed, 347 citations in OpenAlex.
- A novel multifunctional split-type porous biomimetic absorbable mPLA-HA lamina for spinal posterior column reconstruction following laminectomy.Bioactive materials · 2026Article
- Hydroxyapatite/poly-L-lactide mesh tube versus β-tricalcium phosphate granules in locking plate fixation of proximal humeral fractures: a retrospective comparative study.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2026Article
- Giant Direct Magnetoelectric Effect in Nanocomposite CoFeAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- An Overview of Advanced Materials and Manufacturing Strategies for 3D-Printed Bioengineered Vascular Stents: Toward Next-Generation Drug Delivery Applications.Pharmaceutics · 2026Review
- Enhancing the osteogenic potential of 3D-printed polycaprolactone/hydroxyapatite composite scaffolds via in-situ ZIF-8 surface modification.Journal of materials science. Materials in medicine · 2026Article
- Effect of Gamma Irradiation and Simulated Physiological Conditions on the Physicochemical Properties of a 3D-Printed βTCP Composite.Polymers · 2026Article
- Oxidation-degradable resins for 3D-printing of cell-responsive biomaterials.Advanced functional materials · 2025Article
- Synergistic Effect of Poly(ethylenephosphoric Acid) and Cerium in Bone Substitute Composites on Tissue Response and Bone Remodeling.International journal of molecular sciences · 2025Article
- Advancements in biodegradable implants: evaluation in large animal surgical models.Annals of medicine and surgery (2012) · 2025Review
- Alterations in the Physicochemical and Structural Properties of a Ceramic-Polymer Composite Induced by the Substitution of Hydroxyapatite with Fluorapatite.Materials (Basel, Switzerland) · 2025Article
- Production Technologies and Application of Polymer Composites in Engineering: A Review.Polymers · 2025Review
- Biocompatible Thermoplastics in Additive Manufacturing of Bone Defect Fillers: State-of-the-Art and Future Prospects.Materials (Basel, Switzerland) · 2025Review
- The Preparation of a GO/ZnO/nHAp Composite Coating and the Study of Its Performance Optimization for Pure Titanium Implants.Micromachines · 2025Article
- Advances in 3D-printed scaffold technologies for bone defect repair: materials, biomechanics, and clinical prospects.Biomedical engineering online · 2025Review
- Medical Benefits and Polymer Applications of Grapes.Polymers · 2025Review
- Mechanically robust surface-degradable implant from fiber silk composites demonstrates regenerative potential.Bioactive materials · 2025Article
- Fabrication andRSC advances · 2025Article
- Global Advancements in Bioactive Material Manufacturing for Drug Delivery: A Comprehensive Study.ACS omega · 2025Article
- A microenvironment responsive polyetheretherketone implant with antibacterial and osteoimmunomodulatory properties facilitates osseointegration.Bioactive materials · 2025Article
- Piezoelectricity Regulating Immune Osteogenesis in Osteoporosis.BME frontiers · 2025Article
43 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The application of various materials in biomedical procedures has recently experienced rapid growth. One area that is currently receiving significant attention from the scientific community is the treatment of a number of different types of bone-related diseases and disorders by using biodegradable polymer-ceramic composites. Biomaterials, the most common materials used to repair or replace damaged parts of the human body, can be categorized into three major groups: metals, ceramics, and polymers. Composites can be manufactured by combining two or more materials to achieve enhanced biocompatibility and biomechanical properties for specific applications. Biomaterials must display suitable properties for their applications, about strength, durability, and biological influence. Metals and their alloys such as titanium, stainless steel, and cobalt-based alloys have been widely investigated for implant-device applications because of their excellent mechanical properties. However, these materials may also manifest biological issues such as toxicity, poor tissue adhesion and stress shielding effect due to their high elastic modulus. To mitigate these issues, hydroxyapatite (HA) coatings have been used on metals because their chemical composition is similar to that of bone and teeth. Recently, a wide range of synthetic polymers such as poly (l-lactic acid) and poly (l-lactide-
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.