Evidence map›Paper›PMID 30533474›Full record

ArticleGynecologic oncology reports2018

hCG production by mucinous adenocarcinoma of the ovary in a reproductive aged woman.

Vincent Wagner, Heather Winn, Andreea Newtson, David Bender, Megan McDonald

Open access · goldAbstract readCase Reports
In one paragraph

Article in Gynecologic oncology reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.0field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Mucinous Cancer of the Ovary: Overview and Current Status.Diagnostics (Basel, Switzerland) · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Vincent WagnerDivision of General Obstetrics and Gynecology, The University of Iowa Hospitals and Clinics, United States.
Heather WinnDivision of General Obstetrics and Gynecology, The University of Iowa Hospitals and Clinics, United States.
Andreea NewtsonDivision of Gynecologic Oncology, The University of Iowa Hospitals and Clinics, United States.
David BenderDivision of Gynecologic Oncology, The University of Iowa Hospitals and Clinics, United States.
Megan McDonaldDivision of Gynecologic Oncology, The University of Iowa Hospitals and Clinics, United States.
University of Iowa Hospitals and Clinics · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

When elevated serum hCG is discovered during the work up of a gynecologic tumor, it is paramount to identify the source of hCG prior to initiation of treatment. Potential sources of hCG include viable intrauterine pregnancy, ectopic pregnancy, miscarriage, gestational trophoblastic disease, pituitary hCG production, phantom hCG (heterophilic antibody interference), and tumor production. Here, we present a case of elevated hCG in a young women with a large complex pelvic mass. Prior to treatment initiation, the patient underwent work up for hCG elevation, which was ultimately found to be from tumor production. Pathologic examination revealed the mass to be a mucinous adenocarcinoma of the ovary with aberrant expression of hCG, rather than the more typical hCG producing germ cell tumor. We detail the preoperative evaluation process of hCG elevation. Additionally, we discuss the role of hCG in ovarian cancer and influence on tumorigenesis and management.

Indexed as

Epithelial ovarian cancerhCGMucinous ovarian adenocarcinoma

Identifiers

PMID30533474
PMCPMC6258238
OpenAlexW2899479354

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.