ReviewJournal of orthopaedic translation2018
Quantitative analysis of skeletal muscle by computed tomography imaging-State of the art.
Review in Journal of orthopaedic translation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 166 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
166 citing papers in PubMed, 5 syntheses or guidelines pooled it, 228 citations in OpenAlex.
- A Systematic Review and Meta-Analysis of Perioperative Muscle Wasting Following Major Abdominal Surgery.Journal of cachexia, sarcopenia and muscle · 2026Pooled it
- The impact of sarcopenia on sarcoma patients: a systematic review and meta-analysis.La Radiologia medica · 2025Pooled it
- Is fatty infiltration in paraspinal muscles reversible with exercise in people with low back pain? A systematic review.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2023Pooled it
- Skeletal Muscle Changes in the First Three Months of Stroke Recovery: A Systematic Review.Journal of rehabilitation medicine · 2022Pooled it
- Imaging Evaluation of Fat Infiltration in Paraspinal Muscles on MRI: A Systematic Review with a Focus on Methodology.Orthopaedic surgery · 2021Pooled it
- Medium-Chain Triglyceride Dietary Supplements Reduce Glucose Metabolism of Gait-Related Skeletal Muscle in Older Adults: A LongitudinalNutrients · 2025Trial
- Trial
- Paraspinal muscle CT measurements in predicting subsequent fractures after percutaneous kyphoplasty in elderly women.North American Spine Society journal · 2026Article
- Muscle volume, CT attenuation, and bone mineral density in relation to trochanteric fragment formation in older women with intertrochanteric femur fractures.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2026Article
- AutoLMISeg: A Fully Automated Pipeline for 3D Lumbar Muscle Volumetry and Densitometry on CT - Technical Validation Against an Operator-Driven Workflow.Journal of imaging informatics in medicine · 2026Article
- The Anatomy of Facial Muscles Revisited: High-Resolution Magnetic Resonance Imaging and Computed Tomography Studies on Body Donors.Journal of imaging · 2026Article
- Consensus recommendations on age-related sarcopenia in South Asia: A nutrition-focused approach.Osteoporosis and sarcopenia · 2026Review
- Sex-specific patterns of skeletal muscle aging at the L3 level: a quantitative study based on opportunistic CT.BMC musculoskeletal disorders · 2026Article
- Reference values and cut-points for trunk myopenia and myosteatosis in Chinese adults: a secondary analysis of the China Action on Spine and Hip study.Quantitative imaging in medicine and surgery · 2026Article
- Lower Preoperative Skeletal Muscle Index in Patients with Pathological T4 Colorectal Cancer: An Exploratory Retrospective Cohort Study.Medical sciences (Basel, Switzerland) · 2026Observational
- Postoperative abdominal bulging after eTEP rives-stoppa repair despite posterior rectus sheath closure: a CT-based ellipse 9 study.Hernia : the journal of hernias and abdominal wall surgery · 2026Observational
- A two-stage deep-learning model using MobileNetV2 and U-Net for CT-based muscle volume assessment in total hip arthroplasty.Scientific reports · 2026Article
- Association of CT-derived muscle quality with multiple geriatric syndromes in older adults: a cross-sectional study.GeroScience · 2026Article
- Photon-counting CT for paraspinal muscle fat quantification compared with MRI proton density fat fraction.BMC medical imaging · 2026Article
- Clinical significance and future applications of standardized imaging parameters for assessing paraspinal muscle fatty infiltration in lumbar degenerative disease: a narrative review.Journal of orthopaedic surgery and research · 2026Review
106 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The radiological assessment of muscle properties-size, mass, density (also termed radiodensity), composition, and adipose tissue infiltration-is fundamental in muscle diseases. More recently, it also became obvious that muscle atrophy, also termed muscle wasting, is caused by or associated with many other diseases or conditions, such as inactivity, malnutrition, chronic obstructive pulmonary disorder, cancer-associated cachexia, diabetes, renal and cardiac failure, and sarcopenia and even potentially with osteoporotic hip fracture. Several techniques have been developed to quantify muscle morphology and function. This review is dedicated to quantitative computed tomography (CT) of skeletal muscle and only includes a brief comparison with magnetic resonance imaging. Strengths and limitations of CT techniques are discussed in detail, including CT scanner calibration, acquisition and reconstruction protocols, and the various quantitative parameters that can be measured with CT, starting from simple volume measures to advanced parameters describing the adipose tissue distribution within muscle. Finally, the use of CT in sarcopenia and cachexia and the relevance of muscle parameters for the assessment of osteoporotic fracture illustrate the application of CT in two emerging areas of medical interest.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.