Evidence map›Paper›PMID 30533206›Full record

ReviewEuropean clinical respiratory journal2018

Efficacy, adverse events, and inter-drug comparison of mepolizumab and reslizumab anti-IL-5 treatments of severe asthma - a systematic review and meta-analysis.

Daniel P Henriksen, Uffe Bodtger, Kirsten Sidenius, Niels Maltbaek, Lars Pedersen, Hanne Madsen, Ehm A Andersson, Ole Norgaard, Louise Klokker Madsen, Bo L Chawes

Open access · goldAbstract readReview
In one paragraph

Review in European clinical respiratory journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 3 pooled it
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 3 syntheses or guidelines pooled it, 58 citations in OpenAlex.

  1. Anti-IL-5 therapies for asthma.The Cochrane database of systematic reviews · 2022
    Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Trial
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Review
  13. Article
  14. Specific Therapy for T2 Asthma.Journal of personalized medicine · 2022
    Review
  15. Article
  16. Review
  17. Pneumo news · 2022
    Review
  18. Variability ofThe World Allergy Organization journal · 2021
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 1 country.

Daniel P HenriksenDepartment of Clinical Biochemistry and Pharmacology, Odense University Hospital, Odense, Denmark.ORCID 0000-0003-1303-6195
Uffe BodtgerDepartment of Respiratory Medicine, Næstved Hospital, Næstved, Denmark.ORCID 0000-0002-1231-9209
Kirsten SideniusAllergi og Lungeklinikken Helsingør, Helsingør, Denmark.
Niels MaltbaekDepartment of Medicine, Zealand University Hospital, Roskilde, Denmark.
Lars PedersenDepartment of Respiratory Medicine, Bispebjerg Hospital, Copenhagen, Denmark.
Hanne MadsenDepartment of Respiratory Medicine, Odense University Hospital, Odense, Denmark.
Ehm A AnderssonThe Danish Medicines Council Secretariat, Copenhagen, Denmark.
Ole NorgaardThe Danish Medicines Council Secretariat, Copenhagen, Denmark.ORCID 0000-0002-1681-4338
Louise Klokker MadsenThe Danish Medicines Council Secretariat, Copenhagen, Denmark.ORCID 0000-0003-2463-0990
Bo L ChawesCOPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0001-6846-6243
Danish Medicines Agency · DKOdense University Hospital · DKBispebjerg Hospital · DKNæstved Sygehus · DKUniversity of Copenhagen · DKZealand University Hospital · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

anti-IL-5mepolizumabreslizumabSevere asthmasystematic review

Identifiers

PMID30533206
PMCPMC6282428
OpenAlexW2899827635

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.