Evidence map›Paper›PMID 30533173›Full record

ArticleOxidative medicine and cellular longevity2018

Geniposide Protects against Obesity-Related Cardiac Injury through AMPK

Zhen-Guo Ma, Chun-Yan Kong, Peng Song, Xin Zhang, Yu-Pei Yuan, Qi-Zhu Tang

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 40 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 3 countries.

Zhen-Guo MaDepartment of Cardiology, Renmin Hospital of Wuhan University, Wuhan 430060, China.
Chun-Yan KongDepartment of Cardiology, Renmin Hospital of Wuhan University, Wuhan 430060, China.
Peng SongDepartment of Cardiology, Renmin Hospital of Wuhan University, Wuhan 430060, China.
Xin ZhangDepartment of Cardiology, Renmin Hospital of Wuhan University, Wuhan 430060, China.
Yu-Pei YuanDepartment of Cardiology, Renmin Hospital of Wuhan University, Wuhan 430060, China.
Qi-Zhu TangDepartment of Cardiology, Renmin Hospital of Wuhan University, Wuhan 430060, China.ORCID 0000-0003-2210-3169
Cardiovascular Institute Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Our previous study found that geniposide, an agonist of glucagon-like peptide-1 receptor (GLP-1R), protected against cardiac hypertrophy via the activation of AMP-activated protein kinase

Indexed as

AMP-Activated Protein KinasesAnimalsAnti-Inflammatory AgentsCardiomegalyDiet, High-FatHeartInflammationIridoidsMaleMiceMice, Inbred C57BLMyocytes, CardiacObesitySignal TransductionSirtuin 1AMP-Activated Protein KinasesAnti-Inflammatory AgentsgeniposideIridoidsSirt1 protein, mouseSirtuin 1

Identifiers

PMID30533173
PMCPMC6247476
OpenAlexW2898986425

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.