ArticlePloS one2018
Medication adherence among patients with Type 2 diabetes: A mixed methods study.
Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.
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Who cites it
52 citing papers in PubMed.
- The influence of pharmacist-led collaborative care on clinical outcomes in type 2 diabetes mellitus: a multicenter randomized control trial.Frontiers in public health · 2024Trial
- Review
- The association between diabetes knowledge and medication adherence among patients in Saudi Arabia.Pakistan journal of medical sciences · 2026Article
- Development and Psychometric Validation of the ASMA Medication Adherence Questionnaire for Adults with Type 2 Diabetes in Saudi Arabia: A Cross-Sectional Study.Patient preference and adherence · 2026Article
- Barriers to, and enablers of, medication taking among Chinese adults living with type 2 diabetes mellitus in Australia: a qualitative study.International journal of clinical pharmacy · 2025Article
- Article
- Medication adherence and illness perception among diabetic patients in Upper Egypt.BMC endocrine disorders · 2025Article
- Self-Management Behaviours in Type 2 Diabetes Across Gulf Cooperation Council Countries: An Updated Narrative Review to Enhance Patient Care.Healthcare (Basel, Switzerland) · 2025Review
- Drug utilization pattern among type II diabetic patients in Palestine.BMC health services research · 2025Article
- Optimizing risk management for post-amputation wound complications in diabetic patients: Focus on glycemic and immunosuppressive control.World journal of diabetes · 2025Article
- Paramedics and emergency medical technicians' perceptions of geriatric trauma care in Saudi Arabia.BMC emergency medicine · 2025Article
- Article
- Association Between Adherence to Oral Antidiabetic Medications and Cost Sharing Among Patients with Type II Diabetes: A Cross-Sectional Study.Patient preference and adherence · 2025Article
- Exploring Saudi paramedics' experiences in managing adult trauma cases: a qualitative study.BMC emergency medicine · 2024Article
- Adherence to Parkinson's disease medication: A case study to illustrate reasons for non-adherence, implications for practice and engaging under-represented participants in research.Exploratory research in clinical and social pharmacy · 2024Article
- Prevalence of medication adherence and glycemic control among patients with type 2 diabetes and influencing factors: A cross-sectional study.Global epidemiology · 2023Article
- The underutilization of preventive cardiovascular measures in patients with cancer: an analysis of the Behavioural Risk Factor Surveillance System, 2011-22.European journal of preventive cardiology · 2023Article
- Using the theoretical domains framework to determine the barriers and facilitators to medication adherence in Parkinson's disease.Exploratory research in clinical and social pharmacy · 2023Article
- Use of a Smartphone-Based Medication Adherence Platform to Improve Outcomes in Uncontrolled Type 2 Diabetes Among Veterans: Prospective Case-Crossover Study.JMIR diabetes · 2023Article
- Mesenteric fat cryolipolysis attenuates insulin resistance in the Ossabaw swine model of the metabolic syndrome.Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery · 2023Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
objectiveOral hypoglycemic agents (OHAs) are highly effective in managing Type 2 diabetes if taken appropriately. This study assessed adherence to OHAs among patients with Type 2 diabetes and explored factors associated with adherence behaviour. RESEARCH DESIGN AND
methodsMixed methods were used comprising a cross-sectional study using the Arabic version of the Morisky Medication Adherence Scale followed by semi-structured interviews using the Theoretical Domain Framework to explore key determinants of adherence.
resultsThe cross-sectional study included 395 patients of whom 40% achieved a high level of OHA adherence. Lower adherence was associated with younger age (Odds Ratio (OR) 1.084; 95% CI 1.056 to 1.112), higher numbers of non-OHAs (OR 0.848; 95% CI 0.728 to 0.986) and higher HbA1c levels (OR 0.808; 95% CI 0.691 to 0.943). Semi structured interviews based on the Theoretical Domain Framework were completed with 20 patients and identified a wide range of factors potentially associated with OHA adherence, particularly behavioural related factors (e.g. scheduling medication intake, ability to develop a habitual behaviour), social influences (e.g. acting as a role model, the effect of family support), and gaps in knowledge about diabetes and its management with OHAs.
conclusionsThis unique mixed-methods study has highlighted possible reasons for the low levels of OHA adherence in this patient population. Whilst the theoretically-derived determinants of behaviour illustrate the complexities associated with OHA adherence, they also provide a robust underpinning for future intervention(s) development to improve adherence and maximise patient health outcomes.
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